Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
78 cases with simple somatic mutation data · 78 cases total · 2026-01-13 · mapped to Cutaneous Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | BRAF |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 67 |
| 78 |
| 85.9% |
| cbioportal |
| 2 | TTN | Ssm | 60 | 78 | 76.9% | cbioportal |
| 3 | MUC16 | Ssm | 53 | 78 | 67.9% | cbioportal |
| 4 | PRB2 | Ssm | 38 | 78 | 48.7% | cbioportal |
| 5 | CRIPAK | Ssm | 31 | 78 | 39.7% | cbioportal |
| 6 | PRG4 | Ssm | 31 | 78 | 39.7% | cbioportal |
| 7 | ANKRD30A | Ssm | 29 | 78 | 37.2% | cbioportal |
| 9 | TCHH | Ssm | 29 | 78 | 37.2% | cbioportal |
| 10 | TRIOBP | Ssm | 29 | 78 | 37.2% | cbioportal |
| 8 | MUC17 | Ssm | 29 | 78 | 37.2% | cbioportal |
| 12 | PCLO | Ssm | 27 | 78 | 34.6% | cbioportal |
| 11 | DNAH7 | Ssm | 27 | 78 | 34.6% | cbioportal |
| 13 | ZNF208 | Ssm | 27 | 78 | 34.6% | cbioportal |
| 16 | DCC | Ssm | 26 | 78 | 33.3% | cbioportal |
| 23 | ZAN | Ssm | 26 | 78 | 33.3% | cbioportal |
| 15 | CSMD1 | Ssm | 26 | 78 | 33.3% | cbioportal |
| 19 | LRP2 | Ssm | 26 | 78 | 33.3% | cbioportal |
| 18 | LRP1B | Ssm | 26 | 78 | 33.3% | cbioportal |
| 20 | MAGEC1 | Ssm | 26 | 78 | 33.3% | cbioportal |
| 17 | FAT4 | Ssm | 26 | 78 | 33.3% | cbioportal |
| 21 | NEB | Ssm | 26 | 78 | 33.3% | cbioportal |
| 14 | ADGRV1 | Ssm | 26 | 78 | 33.3% | cbioportal |
| 22 | RP1 | Ssm | 26 | 78 | 33.3% | cbioportal |
| 24 | DNAH5 | Ssm | 25 | 78 | 32.1% | cbioportal |
| 25 | FRG1BP | Ssm | 25 | 78 | 32.1% | cbioportal |
| 26 | MUC4 | Ssm | 25 | 78 | 32.1% | cbioportal |
| 27 | CACNA1E | Ssm | 24 | 78 | 30.8% | cbioportal |
| 28 | RYR1 | Ssm | 24 | 78 | 30.8% | cbioportal |
| 31 | GRIN2A | Ssm | 23 | 78 | 29.5% | cbioportal |
| 32 | MACF1 | Ssm | 23 | 78 | 29.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13