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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
29 cases with simple somatic mutation data · 29 cases total · 2026-01-08 · mapped to Myelodysplastic Syndrome EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TET2 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 8 |
| 29 |
| 27.6% |
| cbioportal |
| 2 | U2AF1 | Ssm | 5 | 29 | 17.2% | cbioportal |
| 3 | ZRSR2 | Ssm | 5 | 29 | 17.2% | cbioportal |
| 5 | SRSF2 | Ssm | 3 | 29 | 10.3% | cbioportal |
| 4 | NRAS | Ssm | 3 | 29 | 10.3% | cbioportal |
| 11 | TP53 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 9 | EZH2 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 7 | BCOR | Ssm | 2 | 29 | 6.9% | cbioportal |
| 8 | DNMT3A | Ssm | 2 | 29 | 6.9% | cbioportal |
| 6 | ASXL1 | Ssm | 2 | 29 | 6.9% | cbioportal |
| 10 | KRAS | Ssm | 2 | 29 | 6.9% | cbioportal |
| 23 | ATM | Ssm | 1 | 29 | 3.4% | cbioportal |
| 24 | ATP1A2 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 25 | ATP6V0A2 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 26 | ATRX | Ssm | 1 | 29 | 3.4% | cbioportal |
| 27 | BRCC3 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 28 | BTBD10 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 29 | C1QTNF3 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 30 | CACNA1E | Ssm | 1 | 29 | 3.4% | cbioportal |
| 31 | CALCR | Ssm | 1 | 29 | 3.4% | cbioportal |
| 32 | CASR | Ssm | 1 | 29 | 3.4% | cbioportal |
| 33 | CATSPERD | Ssm | 1 | 29 | 3.4% | cbioportal |
| 34 | CATSPERE | Ssm | 1 | 29 | 3.4% | cbioportal |
| 35 | CBL | Ssm | 1 | 29 | 3.4% | cbioportal |
| 36 | CCDC175 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 37 | CCDC7 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 38 | CCDC83 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 39 | CDH11 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 40 | CEP128 | Ssm | 1 | 29 | 3.4% | cbioportal |
| 41 | CHD7 | Ssm | 1 | 29 | 3.4% | cbioportal |
Data updated 21 days agoSource updated 2026-01-08