Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,075 cases with simple somatic mutation data · 1,154 cases total · 2026-02-19 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SF3B1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 174 |
| 1,075 |
| 16.2% |
| cbioportal |
| 2 | ATM | Ssm | 111 | 1,075 | 10.3% | cbioportal |
| 3 | TP53 | Ssm | 91 | 1,075 | 8.5% | cbioportal |
| 4 | TTN | Ssm | 76 | 1,075 | 7.1% | cbioportal |
| 5 | POT1 | Ssm | 60 | 1,075 | 5.6% | cbioportal |
| 6 | PCLO | Ssm | 58 | 1,075 | 5.4% | cbioportal |
| 7 | CHD2 | Ssm | 55 | 1,075 | 5.1% | cbioportal |
| 8 | NOTCH1 | Ssm | 54 | 1,075 | 5% | cbioportal |
| 9 | XPO1 | Ssm | 51 | 1,075 | 4.7% | cbioportal |
| 10 | MUC16 | Ssm | 49 | 1,075 | 4.6% | cbioportal |
| 11 | LRP1B | Ssm | 48 | 1,075 | 4.5% | cbioportal |
| 12 | CSMD3 | Ssm | 42 | 1,075 | 3.9% | cbioportal |
| 13 | USH2A | Ssm | 37 | 1,075 | 3.4% | cbioportal |
| 14 | FAT4 | Ssm | 35 | 1,075 | 3.3% | cbioportal |
| 17 | RYR2 | Ssm | 34 | 1,075 | 3.2% | cbioportal |
| 16 | MGA | Ssm | 34 | 1,075 | 3.2% | cbioportal |
| 15 | BRAF | Ssm | 34 | 1,075 | 3.2% | cbioportal |
| 20 | MYD88 | Ssm | 33 | 1,075 | 3.1% | cbioportal |
| 19 | FAT1 | Ssm | 33 | 1,075 | 3.1% | cbioportal |
| 18 | EGR2 | Ssm | 33 | 1,075 | 3.1% | cbioportal |
| 21 | ZFHX4 | Ssm | 33 | 1,075 | 3.1% | cbioportal |
| 22 | HMCN1 | Ssm | 32 | 1,075 | 3% | cbioportal |
| 24 | ZNF292 | Ssm | 30 | 1,075 | 2.8% | cbioportal |
| 23 | BIRC3 | Ssm | 30 | 1,075 | 2.8% | cbioportal |
| 25 | DST | Ssm | 28 | 1,075 | 2.6% | cbioportal |
| 26 | CSMD1 | Ssm | 27 | 1,075 | 2.5% | cbioportal |
| 27 | DDX3X | Ssm | 27 | 1,075 | 2.5% | cbioportal |
| 30 | WDFY3 | Ssm | 27 | 1,075 | 2.5% | cbioportal |
| 28 | FBXW7 | Ssm | 27 | 1,075 | 2.5% | cbioportal |
| 29 | KRAS | Ssm | 27 | 1,075 | 2.5% | cbioportal |
Data updated 21 days agoSource updated 2026-02-19