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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
41 cases with simple somatic mutation data · 41 cases total · 2026-01-12 · mapped to Lung Non-Small Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 22 |
| 41 |
| 53.7% |
| cbioportal |
| 2 | EGFR | Ssm | 12 | 41 | 29.3% | cbioportal |
| 3 | KRAS | Ssm | 10 | 41 | 24.4% | cbioportal |
| 4 | ATM | Ssm | 6 | 41 | 14.6% | cbioportal |
| 5 | STK11 | Ssm | 5 | 41 | 12.2% | cbioportal |
| 6 | PIK3CA | Ssm | 4 | 41 | 9.8% | cbioportal |
| 8 | FGFR3 | Ssm | 3 | 41 | 7.3% | cbioportal |
| 9 | KDR | Ssm | 3 | 41 | 7.3% | cbioportal |
| 10 | KIT | Ssm | 3 | 41 | 7.3% | cbioportal |
| 11 | MET | Ssm | 3 | 41 | 7.3% | cbioportal |
| 7 | BRAF | Ssm | 3 | 41 | 7.3% | cbioportal |
| 12 | SMAD4 | Ssm | 3 | 41 | 7.3% | cbioportal |
| 19 | VHL | Ssm | 2 | 41 | 4.9% | cbioportal |
| 16 | PTPN11 | Ssm | 2 | 41 | 4.9% | cbioportal |
| 17 | RB1 | Ssm | 2 | 41 | 4.9% | cbioportal |
| 18 | RET | Ssm | 2 | 41 | 4.9% | cbioportal |
| 13 | APC | Ssm | 2 | 41 | 4.9% | cbioportal |
| 14 | CDH1 | Ssm | 2 | 41 | 4.9% | cbioportal |
| 15 | CDKN2A | Ssm | 2 | 41 | 4.9% | cbioportal |
| 27 | IDH1 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 21 | AKT1 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 22 | ERBB2 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 23 | ERBB4 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 24 | FGFR2 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 25 | FLT3 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 26 | HNF1A | Ssm | 1 | 41 | 2.4% | cbioportal |
| 20 | ABL1 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 28 | NOTCH1 | Ssm | 1 | 41 | 2.4% | cbioportal |
| 29 | SMO | Ssm | 1 | 41 | 2.4% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12