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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
22 cases with simple somatic mutation data · 22 cases total · 2026-01-12 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 21 |
| 22 |
| 95.5% |
| cbioportal |
| 2 | IDH1 | Ssm | 16 | 22 | 72.7% | cbioportal |
| 3 | CIC | Ssm | 13 | 22 | 59.1% | cbioportal |
| 4 | NOTCH1 | Ssm | 6 | 22 | 27.3% | cbioportal |
| 5 | FUBP1 | Ssm | 5 | 22 | 22.7% | cbioportal |
| 6 | NOTCH2 | Ssm | 5 | 22 | 22.7% | cbioportal |
| 9 | HLA-A | Ssm | 4 | 18 | 22.2% | cbioportal |
| 7 | AR | Ssm | 4 | 22 | 18.2% | cbioportal |
| 8 | ERBB4 | Ssm | 4 | 22 | 18.2% | cbioportal |
| 15 | ZFHX3 | Ssm | 3 | 18 | 16.7% | cbioportal |
| 13 | PIK3CA | Ssm | 3 | 22 | 13.6% | cbioportal |
| 10 | BRCA1 | Ssm | 3 | 22 | 13.6% | cbioportal |
| 11 | CDKN2C | Ssm | 3 | 22 | 13.6% | cbioportal |
| 14 | SETD2 | Ssm | 3 | 22 | 13.6% | cbioportal |
| 12 | PALB2 | Ssm | 3 | 22 | 13.6% | cbioportal |
| 28 | FOXO1 | Ssm | 2 | 18 | 11.1% | cbioportal |
| 37 | MGA | Ssm | 2 | 18 | 11.1% | cbioportal |
| 43 | PLCG2 | Ssm | 2 | 18 | 11.1% | cbioportal |
| 44 | POLD1 | Ssm | 2 | 18 | 11.1% | cbioportal |
| 32 | KDM6A | Ssm | 2 | 22 | 9.1% | cbioportal |
| 18 | ATM | Ssm | 2 | 22 | 9.1% | cbioportal |
| 31 | KDM5C | Ssm | 2 | 22 | 9.1% | cbioportal |
| 23 | CSF1R | Ssm | 2 | 22 | 9.1% | cbioportal |
| 51 | SUFU | Ssm | 2 | 22 | 9.1% | cbioportal |
| 33 | KMT2A | Ssm | 2 | 22 | 9.1% | cbioportal |
| 17 | ARID2 | Ssm | 2 | 22 | 9.1% | cbioportal |
| 52 | TSC1 | Ssm | 2 | 22 | 9.1% | cbioportal |
| 53 | TSC2 | Ssm | 2 | 22 | 9.1% | cbioportal |
| 54 | WT1 | Ssm | 2 | 22 | 9.1% | cbioportal |
| 40 | NF1 | Ssm | 2 | 22 | 9.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12