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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
16 cases with simple somatic mutation data · 16 cases total · 2026-02-16 · mapped to Clear Cell Renal Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| SETD2 |
| Ssm |
| 10 |
| 16 |
| 62.5% |
| cbioportal |
| 2 | VHL | Ssm | 8 | 16 | 50% | cbioportal |
| 3 | PBRM1 | Ssm | 6 | 16 | 37.5% | cbioportal |
| 6 | ZFC3H1 | Ssm | 4 | 16 | 25% | cbioportal |
| 4 | BTG4 | Ssm | 4 | 16 | 25% | cbioportal |
| 5 | FBXL13 | Ssm | 4 | 16 | 25% | cbioportal |
| 21 | TTN | Ssm | 3 | 16 | 18.8% | cbioportal |
| 20 | SYNE1 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 19 | SRPK1 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 18 | SPEF2 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 9 | DMXL2 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 16 | SCUBE2 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 15 | PRKDC | Ssm | 3 | 16 | 18.8% | cbioportal |
| 14 | MYO10 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 13 | LRP2 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 12 | HUWE1 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 11 | HEATR1 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 10 | FNDC1 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 17 | SLC9A9 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 23 | VCPIP1 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 8 | CENPB | Ssm | 3 | 16 | 18.8% | cbioportal |
| 7 | ARHGAP39 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 22 | UBR4 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 24 | WDR47 | Ssm | 3 | 16 | 18.8% | cbioportal |
| 152 | ZSWIM2 | Ssm | 2 | 16 | 12.5% | cbioportal |
| 25 | ABCA5 | Ssm | 2 | 16 | 12.5% | cbioportal |
| 26 | ABCC2 | Ssm | 2 | 16 | 12.5% | cbioportal |
| 27 | ADAMTS20 | Ssm | 2 | 16 | 12.5% | cbioportal |
| 28 | ADAMTSL3 | Ssm | 2 | 16 | 12.5% | cbioportal |
| 29 | ADAR | Ssm | 2 | 16 | 12.5% | cbioportal |
Data updated 21 days agoSource updated 2026-02-16