Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
484 cases with simple somatic mutation data · 487 cases total · 2026-06-04 · mapped to Lung Squamous Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | TP53 | Ssm | 404 | 484 | 83.5% | cbioportal |
| 2 | TTN | Ssm | 345 | 484 | 71.3% | cbioportal |
| 3 | CSMD3 | Ssm | 209 | 484 | 43.2% | cbioportal |
| 4 | RYR2 | Ssm | 192 | 484 | 39.7% | cbioportal |
| 5 | MUC16 | Ssm | 188 | 484 | 38.8% | cbioportal |
| 6 | LRP1B | Ssm | 171 | 484 | 35.3% | cbioportal |
| 7 | USH2A | Ssm | 160 | 484 | 33.1% | cbioportal |
| 8 | SYNE1 | Ssm | 151 | 484 | 31.2% | cbioportal |
| 9 | ZFHX4 | Ssm | 143 | 484 | 29.5% | cbioportal |
| 10 | FAM135B | Ssm | 118 | 484 | 24.4% | cbioportal |
| 11 | KMT2D | Ssm | 111 | 484 | 22.9% | cbioportal |
| 12 | NAV3 | Ssm | 104 | 484 | 21.5% | cbioportal |
| 13 | RYR3 | Ssm | 99 | 484 | 20.5% | cbioportal |
| 15 | SPTA1 | Ssm | 97 | 484 | 20% | cbioportal |
| 14 | CDH10 | Ssm | 97 | 484 | 20% | cbioportal |
| 17 | PCDH15 | Ssm | 93 | 484 | 19.2% | cbioportal |
| 18 | XIRP2 | Ssm | 93 | 484 | 19.2% | cbioportal |
| 16 | DNAH5 | Ssm | 93 | 484 | 19.2% | cbioportal |
| 19 | PKHD1L1 | Ssm | 91 | 484 | 18.8% | cbioportal |
| 20 | PAPPA2 | Ssm | 89 | 484 | 18.4% | cbioportal |
| 21 | PCLO | Ssm | 88 | 484 | 18.2% | cbioportal |
| 22 | PKHD1 | Ssm | 87 | 484 | 18% | cbioportal |
| 24 | ERICH3 | Ssm | 84 | 484 | 17.4% | cbioportal |
| 25 | FLG | Ssm | 84 | 484 | 17.4% | cbioportal |
| 26 | SI | Ssm | 84 | 484 | 17.4% | cbioportal |
| 23 | COL11A1 | Ssm | 84 | 484 | 17.4% | cbioportal |
| 27 | COL22A1 | Ssm | 83 | 484 | 17.1% | cbioportal |
| 28 | DNAH8 | Ssm | 83 | 484 | 17.1% | cbioportal |
| 29 | RYR1 | Ssm | 83 | 484 | 17.1% | cbioportal |
| 30 | CSMD1 | Ssm | 82 | 484 | 16.9% | cbioportal |
Data updated 21 days agoSource updated 2026-06-04