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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
247 cases with simple somatic mutation data · 442 cases total · 2026-01-14 · mapped to Endometrial Endometrioid Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | PTEN | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 194 |
| 247 |
| 78.5% |
| cbioportal |
| 2 | ARID1A | Ssm | 136 | 247 | 55.1% | cbioportal |
| 3 | PIK3CA | Ssm | 105 | 247 | 42.5% | cbioportal |
| 4 | PIK3R1 | Ssm | 91 | 247 | 36.8% | cbioportal |
| 5 | TTN | Ssm | 89 | 247 | 36% | cbioportal |
| 6 | CTNNB1 | Ssm | 71 | 247 | 28.7% | cbioportal |
| 7 | KRAS | Ssm | 67 | 247 | 27.1% | cbioportal |
| 8 | OBSCN | Ssm | 65 | 247 | 26.3% | cbioportal |
| 9 | KMT2B | Ssm | 62 | 247 | 25.1% | cbioportal |
| 10 | INPPL1 | Ssm | 61 | 247 | 24.7% | cbioportal |
| 12 | TP53 | Ssm | 61 | 247 | 24.7% | cbioportal |
| 11 | KMT2D | Ssm | 61 | 247 | 24.7% | cbioportal |
| 13 | CTCF | Ssm | 56 | 247 | 22.7% | cbioportal |
| 15 | ZFHX3 | Ssm | 54 | 247 | 21.9% | cbioportal |
| 14 | SYNE1 | Ssm | 54 | 247 | 21.9% | cbioportal |
| 16 | PCLO | Ssm | 51 | 247 | 20.6% | cbioportal |
| 17 | MUC16 | Ssm | 49 | 247 | 19.8% | cbioportal |
| 18 | MUC5B | Ssm | 48 | 247 | 19.4% | cbioportal |
| 19 | FSIP2 | Ssm | 47 | 247 | 19% | cbioportal |
| 20 | CSMD3 | Ssm | 46 | 247 | 18.6% | cbioportal |
| 21 | RYR1 | Ssm | 45 | 247 | 18.2% | cbioportal |
| 22 | ZFHX4 | Ssm | 45 | 247 | 18.2% | cbioportal |
| 23 | JAK1 | Ssm | 43 | 247 | 17.4% | cbioportal |
| 24 | RYR2 | Ssm | 43 | 247 | 17.4% | cbioportal |
| 25 | DNAH5 | Ssm | 42 | 247 | 17% | cbioportal |
| 27 | FAT3 | Ssm | 41 | 247 | 16.6% | cbioportal |
| 28 | HERC2 | Ssm | 41 | 247 | 16.6% | cbioportal |
| 26 | CHD4 | Ssm | 41 | 247 | 16.6% | cbioportal |
| 31 | LRTM3 | Ssm | 40 | 247 | 16.2% | cbioportal |
| 29 | DNAH17 | Ssm | 40 | 247 | 16.2% | cbioportal |
Data updated 21 days agoSource updated 2026-01-14