Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
302 cases with simple somatic mutation data · 305 cases total · 2026-01-07 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | EGFR |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 143 |
| 302 |
| 47.4% |
| cbioportal |
| 2 | TP53 | Ssm | 109 | 302 | 36.1% | cbioportal |
| 3 | TTN | Ssm | 68 | 302 | 22.5% | cbioportal |
| 4 | RYR2 | Ssm | 50 | 302 | 16.6% | cbioportal |
| 5 | USH2A | Ssm | 50 | 302 | 16.6% | cbioportal |
| 6 | MUC16 | Ssm | 46 | 302 | 15.2% | cbioportal |
| 7 | CSMD3 | Ssm | 43 | 302 | 14.2% | cbioportal |
| 8 | ZFHX4 | Ssm | 39 | 302 | 12.9% | cbioportal |
| 9 | FLG | Ssm | 37 | 302 | 12.3% | cbioportal |
| 10 | LRP1B | Ssm | 35 | 302 | 11.6% | cbioportal |
| 11 | KRAS | Ssm | 33 | 302 | 10.9% | cbioportal |
| 12 | PCLO | Ssm | 30 | 302 | 9.9% | cbioportal |
| 14 | XIRP2 | Ssm | 30 | 302 | 9.9% | cbioportal |
| 13 | SPTA1 | Ssm | 30 | 302 | 9.9% | cbioportal |
| 15 | ANK2 | Ssm | 29 | 302 | 9.6% | cbioportal |
| 16 | SI | Ssm | 27 | 302 | 8.9% | cbioportal |
| 18 | FAT3 | Ssm | 26 | 302 | 8.6% | cbioportal |
| 19 | MUC17 | Ssm | 26 | 302 | 8.6% | cbioportal |
| 17 | CTNND2 | Ssm | 26 | 302 | 8.6% | cbioportal |
| 22 | CSMD1 | Ssm | 24 | 302 | 7.9% | cbioportal |
| 23 | FAT4 | Ssm | 24 | 302 | 7.9% | cbioportal |
| 20 | AHNAK2 | Ssm | 24 | 302 | 7.9% | cbioportal |
| 21 | COL11A1 | Ssm | 24 | 302 | 7.9% | cbioportal |
| 24 | PRDM9 | Ssm | 24 | 302 | 7.9% | cbioportal |
| 26 | NAV3 | Ssm | 23 | 302 | 7.6% | cbioportal |
| 27 | NEB | Ssm | 23 | 302 | 7.6% | cbioportal |
| 25 | MUC4 | Ssm | 23 | 302 | 7.6% | cbioportal |
| 28 | ZNF536 | Ssm | 23 | 302 | 7.6% | cbioportal |
| 29 | RBM10 | Ssm | 22 | 302 | 7.3% | cbioportal |
| 30 | ADAMTS12 | Ssm | 21 | 302 | 7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07