Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
145 cases with simple somatic mutation data · 145 cases total · 2026-04-07 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 88 |
| 145 |
| 60.7% |
| cbioportal |
| 2 | PIK3CA | Ssm | 42 | 145 | 29% | cbioportal |
| 3 | GATA3 | Ssm | 17 | 145 | 11.7% | cbioportal |
| 4 | CDH1 | Ssm | 12 | 145 | 8.3% | cbioportal |
| 5 | ERBB2 | Ssm | 11 | 145 | 7.6% | cbioportal |
| 6 | NF1 | Ssm | 10 | 145 | 6.9% | cbioportal |
| 7 | KMT2C | Ssm | 9 | 145 | 6.2% | cbioportal |
| 8 | TBX3 | Ssm | 9 | 145 | 6.2% | cbioportal |
| 9 | ARID2 | Ssm | 8 | 145 | 5.5% | cbioportal |
| 10 | ARID1A | Ssm | 7 | 145 | 4.8% | cbioportal |
| 14 | RARA | Ssm | 7 | 145 | 4.8% | cbioportal |
| 13 | PTPRD | Ssm | 7 | 145 | 4.8% | cbioportal |
| 11 | ATM | Ssm | 7 | 145 | 4.8% | cbioportal |
| 12 | ERBB3 | Ssm | 7 | 145 | 4.8% | cbioportal |
| 15 | KMT2D | Ssm | 6 | 145 | 4.1% | cbioportal |
| 23 | ZFHX3 | Ssm | 5 | 122 | 4.1% | cbioportal |
| 16 | ALK | Ssm | 5 | 145 | 3.4% | cbioportal |
| 17 | FAT1 | Ssm | 5 | 145 | 3.4% | cbioportal |
| 20 | RECQL4 | Ssm | 5 | 145 | 3.4% | cbioportal |
| 19 | PTEN | Ssm | 5 | 145 | 3.4% | cbioportal |
| 21 | RUNX1 | Ssm | 5 | 145 | 3.4% | cbioportal |
| 18 | PIK3R1 | Ssm | 5 | 145 | 3.4% | cbioportal |
| 22 | TET1 | Ssm | 5 | 145 | 3.4% | cbioportal |
| 26 | ESR1 | Ssm | 4 | 145 | 2.8% | cbioportal |
| 25 | EPHA5 | Ssm | 4 | 145 | 2.8% | cbioportal |
| 32 | SMAD4 | Ssm | 4 | 145 | 2.8% | cbioportal |
| 24 | BRD4 | Ssm | 4 | 145 | 2.8% | cbioportal |
| 29 | NOTCH4 | Ssm | 4 | 145 | 2.8% | cbioportal |
| 30 | PTPRS | Ssm | 4 | 145 | 2.8% | cbioportal |
| 27 | KMT2A | Ssm | 4 | 145 | 2.8% | cbioportal |
Data updated 21 days agoSource updated 2026-04-07