Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
184 cases with simple somatic mutation data · 184 cases total · 2026-01-05 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TERT |
| Ssm |
| 141 |
| 184 |
| 76.6% |
| cbioportal |
| 2 | TP53 | Ssm | 116 | 184 | 63% | cbioportal |
| 3 | KMT2D | Ssm | 64 | 184 | 34.8% | cbioportal |
| 4 | KDM6A | Ssm | 55 | 184 | 29.9% | cbioportal |
| 5 | ARID1A | Ssm | 50 | 184 | 27.2% | cbioportal |
| 6 | RB1 | Ssm | 48 | 184 | 26.1% | cbioportal |
| 7 | PIK3CA | Ssm | 42 | 184 | 22.8% | cbioportal |
| 8 | KMT2C | Ssm | 35 | 184 | 19% | cbioportal |
| 9 | ATM | Ssm | 31 | 184 | 16.8% | cbioportal |
| 10 | ELF3 | Ssm | 29 | 184 | 15.8% | cbioportal |
| 11 | FAT1 | Ssm | 29 | 184 | 15.8% | cbioportal |
| 13 | ERCC2 | Ssm | 27 | 184 | 14.7% | cbioportal |
| 12 | CREBBP | Ssm | 27 | 184 | 14.7% | cbioportal |
| 14 | BRCA2 | Ssm | 26 | 184 | 14.1% | cbioportal |
| 15 | KMT2A | Ssm | 26 | 184 | 14.1% | cbioportal |
| 16 | ERBB2 | Ssm | 25 | 184 | 13.6% | cbioportal |
| 17 | FGFR3 | Ssm | 25 | 184 | 13.6% | cbioportal |
| 18 | EP300 | Ssm | 24 | 184 | 13% | cbioportal |
| 19 | ERBB3 | Ssm | 24 | 184 | 13% | cbioportal |
| 20 | TSC1 | Ssm | 22 | 184 | 12% | cbioportal |
| 21 | FBXW7 | Ssm | 21 | 184 | 11.4% | cbioportal |
| 22 | CDKN1A | Ssm | 20 | 184 | 10.9% | cbioportal |
| 23 | H3C7 | Ssm | 18 | 184 | 9.8% | cbioportal |
| 25 | STAG2 | Ssm | 18 | 184 | 9.8% | cbioportal |
| 24 | NF1 | Ssm | 18 | 184 | 9.8% | cbioportal |
| 26 | PTPRT | Ssm | 17 | 184 | 9.2% | cbioportal |
| 29 | NSD1 | Ssm | 16 | 184 | 8.7% | cbioportal |
| 28 | KMT2B | Ssm | 16 | 184 | 8.7% | cbioportal |
| 27 | CDKN2A | Ssm | 16 | 184 | 8.7% | cbioportal |
| 30 | ARID1B | Ssm | 15 | 184 | 8.2% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05