Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
383 cases with simple somatic mutation data · 456 cases total · 2026-01-12 · mapped to Pancreatic Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 344 |
| 383 |
| 89.8% |
| cbioportal |
| 2 | TP53 | Ssm | 253 | 383 | 66.1% | cbioportal |
| 3 | SMAD4 | Ssm | 86 | 383 | 22.5% | cbioportal |
| 4 | CDKN2A | Ssm | 71 | 383 | 18.5% | cbioportal |
| 5 | TTN | Ssm | 56 | 383 | 14.6% | cbioportal |
| 6 | ARID1A | Ssm | 29 | 383 | 7.6% | cbioportal |
| 7 | SYNE1 | Ssm | 27 | 383 | 7% | cbioportal |
| 8 | LRP1B | Ssm | 22 | 383 | 5.7% | cbioportal |
| 9 | KMT2C | Ssm | 21 | 383 | 5.5% | cbioportal |
| 11 | RYR1 | Ssm | 21 | 383 | 5.5% | cbioportal |
| 10 | RNF43 | Ssm | 21 | 383 | 5.5% | cbioportal |
| 12 | MUC16 | Ssm | 20 | 383 | 5.2% | cbioportal |
| 15 | KMT2D | Ssm | 19 | 383 | 5% | cbioportal |
| 14 | HMCN1 | Ssm | 19 | 383 | 5% | cbioportal |
| 13 | FLG | Ssm | 19 | 383 | 5% | cbioportal |
| 18 | OBSCN | Ssm | 18 | 383 | 4.7% | cbioportal |
| 19 | TGFBR2 | Ssm | 18 | 383 | 4.7% | cbioportal |
| 17 | GLI3 | Ssm | 18 | 383 | 4.7% | cbioportal |
| 16 | FAT3 | Ssm | 18 | 383 | 4.7% | cbioportal |
| 21 | MUC4 | Ssm | 16 | 383 | 4.2% | cbioportal |
| 20 | DNAH11 | Ssm | 16 | 383 | 4.2% | cbioportal |
| 22 | RYR3 | Ssm | 16 | 383 | 4.2% | cbioportal |
| 23 | RYR2 | Ssm | 15 | 383 | 3.9% | cbioportal |
| 26 | WDFY4 | Ssm | 14 | 383 | 3.7% | cbioportal |
| 24 | ATM | Ssm | 14 | 383 | 3.7% | cbioportal |
| 25 | CSMD1 | Ssm | 14 | 383 | 3.7% | cbioportal |
| 31 | THSD7B | Ssm | 13 | 383 | 3.4% | cbioportal |
| 28 | CSMD3 | Ssm | 13 | 383 | 3.4% | cbioportal |
| 27 | ADGRV1 | Ssm | 13 | 383 | 3.4% | cbioportal |
| 29 | DNAH5 | Ssm | 13 | 383 | 3.4% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12