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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
75 cases with simple somatic mutation data · 75 cases total · 2026-01-12 · mapped to Lung Non-Small Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 42 |
| 75 |
| 56% |
| cbioportal |
| 2 | TTN | Ssm | 36 | 75 | 48% | cbioportal |
| 3 | RYR2 | Ssm | 30 | 75 | 40% | cbioportal |
| 4 | MUC16 | Ssm | 25 | 75 | 33.3% | cbioportal |
| 5 | KRAS | Ssm | 23 | 75 | 30.7% | cbioportal |
| 6 | USH2A | Ssm | 22 | 75 | 29.3% | cbioportal |
| 7 | CSMD3 | Ssm | 20 | 75 | 26.7% | cbioportal |
| 8 | LRP1B | Ssm | 19 | 75 | 25.3% | cbioportal |
| 9 | OBSCN | Ssm | 19 | 75 | 25.3% | cbioportal |
| 10 | XIRP2 | Ssm | 18 | 75 | 24% | cbioportal |
| 11 | ZFHX4 | Ssm | 18 | 75 | 24% | cbioportal |
| 12 | FAT3 | Ssm | 16 | 75 | 21.3% | cbioportal |
| 13 | FLG | Ssm | 16 | 75 | 21.3% | cbioportal |
| 15 | CTNND2 | Ssm | 15 | 75 | 20% | cbioportal |
| 14 | COL22A1 | Ssm | 15 | 75 | 20% | cbioportal |
| 16 | MUC17 | Ssm | 15 | 75 | 20% | cbioportal |
| 22 | FLNC | Ssm | 14 | 75 | 18.7% | cbioportal |
| 19 | DNAH11 | Ssm | 14 | 75 | 18.7% | cbioportal |
| 20 | DNAH5 | Ssm | 14 | 75 | 18.7% | cbioportal |
| 23 | RELN | Ssm | 14 | 75 | 18.7% | cbioportal |
| 17 | ANK2 | Ssm | 14 | 75 | 18.7% | cbioportal |
| 21 | DYNC2H1 | Ssm | 14 | 75 | 18.7% | cbioportal |
| 18 | CACNA1E | Ssm | 14 | 75 | 18.7% | cbioportal |
| 27 | SPTA1 | Ssm | 13 | 75 | 17.3% | cbioportal |
| 26 | PCDH15 | Ssm | 13 | 75 | 17.3% | cbioportal |
| 24 | COL11A1 | Ssm | 13 | 75 | 17.3% | cbioportal |
| 25 | CSMD1 | Ssm | 13 | 75 | 17.3% | cbioportal |
| 28 | SYNE1 | Ssm | 13 | 75 | 17.3% | cbioportal |
| 33 | FSIP2 | Ssm | 12 | 75 | 16% | cbioportal |
| 35 | SI | Ssm | 12 | 75 | 16% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12