Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
491 cases with simple somatic mutation data · 501 cases total · 2026-01-13 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 55 |
| 491 |
| 11.2% |
| cbioportal |
| 2 | SPOP | Ssm | 54 | 491 | 11% | cbioportal |
| 3 | TTN | Ssm | 47 | 491 | 9.6% | cbioportal |
| 4 | FOXA1 | Ssm | 29 | 491 | 5.9% | cbioportal |
| 5 | KMT2D | Ssm | 28 | 491 | 5.7% | cbioportal |
| 6 | MUC16 | Ssm | 26 | 491 | 5.3% | cbioportal |
| 7 | SYNE1 | Ssm | 22 | 491 | 4.5% | cbioportal |
| 8 | KMT2C | Ssm | 21 | 491 | 4.3% | cbioportal |
| 10 | SPTA1 | Ssm | 20 | 491 | 4.1% | cbioportal |
| 9 | LRP1B | Ssm | 20 | 491 | 4.1% | cbioportal |
| 11 | ATM | Ssm | 18 | 491 | 3.7% | cbioportal |
| 12 | CSMD3 | Ssm | 17 | 491 | 3.5% | cbioportal |
| 13 | RYR2 | Ssm | 17 | 491 | 3.5% | cbioportal |
| 14 | PTEN | Ssm | 16 | 491 | 3.3% | cbioportal |
| 15 | KDM6A | Ssm | 15 | 491 | 3.1% | cbioportal |
| 17 | HMCN1 | Ssm | 14 | 491 | 2.9% | cbioportal |
| 16 | CACNA1E | Ssm | 14 | 491 | 2.9% | cbioportal |
| 18 | MUC17 | Ssm | 14 | 491 | 2.9% | cbioportal |
| 19 | RP1 | Ssm | 13 | 491 | 2.6% | cbioportal |
| 20 | USH2A | Ssm | 13 | 491 | 2.6% | cbioportal |
| 21 | FAT3 | Ssm | 12 | 491 | 2.4% | cbioportal |
| 23 | RYR1 | Ssm | 12 | 491 | 2.4% | cbioportal |
| 22 | MYO15A | Ssm | 12 | 491 | 2.4% | cbioportal |
| 27 | CNTNAP5 | Ssm | 11 | 491 | 2.2% | cbioportal |
| 28 | MACF1 | Ssm | 11 | 491 | 2.2% | cbioportal |
| 25 | ADGRB3 | Ssm | 11 | 491 | 2.2% | cbioportal |
| 24 | ABCA13 | Ssm | 11 | 491 | 2.2% | cbioportal |
| 29 | OBSCN | Ssm | 11 | 491 | 2.2% | cbioportal |
| 26 | APC | Ssm | 11 | 491 | 2.2% | cbioportal |
| 30 | ZMYM3 | Ssm | 11 | 491 | 2.2% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13