Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
140 cases with simple somatic mutation data · 140 cases total · 2026-01-12 · mapped to Pancreatic Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 135 |
| 140 |
| 96.4% |
| cbioportal |
| 2 | TP53 | Ssm | 105 | 140 | 75% | cbioportal |
| 3 | CDKN2A | Ssm | 29 | 140 | 20.7% | cbioportal |
| 4 | SMAD4 | Ssm | 24 | 140 | 17.1% | cbioportal |
| 5 | CTNNA2 | Ssm | 13 | 140 | 9.3% | cbioportal |
| 6 | MUC4 | Ssm | 13 | 140 | 9.3% | cbioportal |
| 7 | TTN | Ssm | 12 | 140 | 8.6% | cbioportal |
| 8 | RYR2 | Ssm | 10 | 140 | 7.1% | cbioportal |
| 9 | RNF43 | Ssm | 9 | 140 | 6.4% | cbioportal |
| 10 | ARID1A | Ssm | 8 | 140 | 5.7% | cbioportal |
| 11 | KMT2D | Ssm | 8 | 140 | 5.7% | cbioportal |
| 13 | FMN2 | Ssm | 7 | 140 | 5% | cbioportal |
| 14 | GNAS | Ssm | 7 | 140 | 5% | cbioportal |
| 17 | SYNE1 | Ssm | 7 | 140 | 5% | cbioportal |
| 15 | MUC16 | Ssm | 7 | 140 | 5% | cbioportal |
| 16 | RBMXL3 | Ssm | 7 | 140 | 5% | cbioportal |
| 12 | DNAH9 | Ssm | 7 | 140 | 5% | cbioportal |
| 28 | RYR3 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 27 | RBM10 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 26 | PXDNL | Ssm | 6 | 140 | 4.3% | cbioportal |
| 29 | TAF1L | Ssm | 6 | 140 | 4.3% | cbioportal |
| 25 | LRP1B | Ssm | 6 | 140 | 4.3% | cbioportal |
| 24 | KMT2C | Ssm | 6 | 140 | 4.3% | cbioportal |
| 31 | ZNF717 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 23 | IRX2 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 22 | GLI3 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 21 | DOCK2 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 30 | ZFHX4 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 20 | CSMD1 | Ssm | 6 | 140 | 4.3% | cbioportal |
| 18 | ANKRD30B | Ssm | 6 | 140 | 4.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-12