Neoplasm by Site — Genomics

Neoplasm by Site — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Hereditary SDHB-Mutant Pheochromocytomas and Paragangliomas (A5 Consortium, Nature Comm 2025) hnsc_a5consortium_2025A5 Consortium

94 cases with simple somatic mutation data · 94 cases total · 2026-01-07 · mapped to Head and Neck Squamous Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.

1	SDHB	Ssm	66	94	70.2%	cbioportal
2	TERT	Ssm	18	94	19.1%	cbioportal
3	MUC17	Ssm	13	94	13.8%	cbioportal
4	GTF2I	Ssm	11	94	11.7%	cbioportal
5	TEX13C	Ssm	11	94	11.7%	cbioportal
6	ATRX	Ssm	9	94	9.6%	cbioportal
7	MDC1	Ssm	6	94	6.4%	cbioportal
8	TCHH	Ssm	6	94	6.4%	cbioportal
10	FAM47C	Ssm	5	94	5.3%	cbioportal
12	OBSCN	Ssm	5	94	5.3%	cbioportal
9	BLOC1S5-TXNDC5	Ssm	5	94	5.3%	cbioportal
11	FLG2	Ssm	5	94	5.3%	cbioportal
27	TTN	Ssm	4	94	4.3%	cbioportal
13	ADAMTS2	Ssm	4	94	4.3%	cbioportal
24	PCNT	Ssm	4	94	4.3%	cbioportal
15	BCR	Ssm	4	94	4.3%	cbioportal
14	BCOR	Ssm	4	94	4.3%	cbioportal
16	CACNA1A	Ssm	4	94	4.3%	cbioportal
19	LINC01618	Ssm	4	94	4.3%	cbioportal
25	PRR5-ARHGAP8	Ssm	4	94	4.3%	cbioportal
20	MED12	Ssm	4	94	4.3%	cbioportal
18	DST	Ssm	4	94	4.3%	cbioportal
26	SECISBP2L	Ssm	4	94	4.3%	cbioportal
21	MUC5AC	Ssm	4	94	4.3%	cbioportal
17	CACNA1E	Ssm	4	94	4.3%	cbioportal
22	NBPF11	Ssm	4	94	4.3%	cbioportal
23	NOX5	Ssm	4	94	4.3%	cbioportal
54	KTN1	Ssm	3	94	3.2%	cbioportal
55	LINC02210-CRHR1	Ssm	3	94	3.2%	cbioportal
56	MRPL38	Ssm	3	94	3.2%	cbioportal