Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
887 cases with simple somatic mutation data · 887 cases total · 2026-03-16 · mapped to Acute Myeloid Leukemia EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | NRAS |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 188 |
| 887 |
| 21.2% |
| cbioportal |
| 2 | WT1 | Ssm | 116 | 887 | 13.1% | cbioportal |
| 3 | KIT | Ssm | 88 | 887 | 9.9% | cbioportal |
| 4 | FLT3 | Ssm | 79 | 887 | 8.9% | cbioportal |
| 5 | KRAS | Ssm | 78 | 887 | 8.8% | cbioportal |
| 6 | NPM1 | Ssm | 67 | 887 | 7.6% | cbioportal |
| 7 | PTPN11 | Ssm | 59 | 887 | 6.7% | cbioportal |
| 8 | CEBPA | Ssm | 56 | 887 | 6.3% | cbioportal |
| 9 | ASXL2 | Ssm | 29 | 887 | 3.3% | cbioportal |
| 10 | ZBTB7A | Ssm | 29 | 887 | 3.3% | cbioportal |
| 11 | GATA2 | Ssm | 27 | 887 | 3% | cbioportal |
| 13 | RUNX1 | Ssm | 26 | 887 | 2.9% | cbioportal |
| 12 | NF1 | Ssm | 26 | 887 | 2.9% | cbioportal |
| 15 | SETD2 | Ssm | 22 | 887 | 2.5% | cbioportal |
| 14 | IDH2 | Ssm | 22 | 887 | 2.5% | cbioportal |
| 16 | RAD21 | Ssm | 21 | 887 | 2.4% | cbioportal |
| 17 | TP53 | Ssm | 18 | 887 | 2% | cbioportal |
| 19 | KDM6A | Ssm | 17 | 887 | 1.9% | cbioportal |
| 21 | TET2 | Ssm | 17 | 887 | 1.9% | cbioportal |
| 20 | PHF6 | Ssm | 17 | 887 | 1.9% | cbioportal |
| 18 | GATA1 | Ssm | 17 | 887 | 1.9% | cbioportal |
| 22 | CCND3 | Ssm | 16 | 887 | 1.8% | cbioportal |
| 23 | ASXL1 | Ssm | 15 | 887 | 1.7% | cbioportal |
| 26 | IKZF1 | Ssm | 15 | 887 | 1.7% | cbioportal |
| 25 | EZH2 | Ssm | 15 | 887 | 1.7% | cbioportal |
| 24 | ETV6 | Ssm | 15 | 887 | 1.7% | cbioportal |
| 27 | BCOR | Ssm | 14 | 887 | 1.6% | cbioportal |
| 28 | KMT2C | Ssm | 14 | 887 | 1.6% | cbioportal |
| 29 | MPL | Ssm | 14 | 887 | 1.6% | cbioportal |
| 31 | JAK2 | Ssm | 13 | 887 | 1.5% | cbioportal |
Data updated 21 days agoSource updated 2026-03-16