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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
135 cases with simple somatic mutation data · 135 cases total · 2026-01-07 · mapped to Diffuse Large B-Cell Lymphoma Unclassifiable EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 35 |
| 135 |
| 25.9% |
| cbioportal |
| 2 | PCLO | Ssm | 32 | 135 | 23.7% | cbioportal |
| 4 | TP53 | Ssm | 31 | 135 | 23% | cbioportal |
| 3 | PIM1 | Ssm | 31 | 135 | 23% | cbioportal |
| 5 | BCL2 | Ssm | 30 | 135 | 22.2% | cbioportal |
| 6 | CREBBP | Ssm | 28 | 135 | 20.7% | cbioportal |
| 7 | BTG1 | Ssm | 25 | 135 | 18.5% | cbioportal |
| 8 | MYD88 | Ssm | 22 | 135 | 16.3% | cbioportal |
| 10 | FAT4 | Ssm | 20 | 135 | 14.8% | cbioportal |
| 9 | CD79B | Ssm | 20 | 135 | 14.8% | cbioportal |
| 11 | SGK1 | Ssm | 19 | 135 | 14.1% | cbioportal |
| 12 | CARD11 | Ssm | 18 | 135 | 13.3% | cbioportal |
| 13 | TTN | Ssm | 18 | 135 | 13.3% | cbioportal |
| 14 | FAT1 | Ssm | 17 | 135 | 12.6% | cbioportal |
| 15 | TNFRSF14 | Ssm | 17 | 135 | 12.6% | cbioportal |
| 16 | CSMD3 | Ssm | 16 | 135 | 11.9% | cbioportal |
| 17 | H1-2 | Ssm | 16 | 135 | 11.9% | cbioportal |
| 18 | USH2A | Ssm | 16 | 135 | 11.9% | cbioportal |
| 20 | ZFP36L1 | Ssm | 15 | 135 | 11.1% | cbioportal |
| 19 | ACTB | Ssm | 15 | 135 | 11.1% | cbioportal |
| 21 | H1-4 | Ssm | 14 | 135 | 10.4% | cbioportal |
| 23 | MUC16 | Ssm | 14 | 135 | 10.4% | cbioportal |
| 22 | LRP1B | Ssm | 14 | 135 | 10.4% | cbioportal |
| 26 | TBL1XR1 | Ssm | 13 | 135 | 9.6% | cbioportal |
| 24 | CD70 | Ssm | 13 | 135 | 9.6% | cbioportal |
| 25 | SYNE1 | Ssm | 13 | 135 | 9.6% | cbioportal |
| 36 | TMSB4X | Ssm | 12 | 135 | 8.9% | cbioportal |
| 31 | IGLL5 | Ssm | 12 | 135 | 8.9% | cbioportal |
| 32 | KLHL6 | Ssm | 12 | 135 | 8.9% | cbioportal |
| 34 | MEF2B | Ssm | 12 | 135 | 8.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07