Gene
KSR2
kinase suppressor of ras 2
Explore in graph →CI-GENE-00007506HGNC:18610 ENSG00000171435 NCBI 283455 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (15)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25233892
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Uterine Carcinosarcoma (Johns Hopkins, Nat Commun 2014) ucs_jhu_2014 | Uterine Malignant Mixed Mesodermal (Mullerian) Tumor | Ssm | 4 | 22 | 18.2% | 103 | cbioportal |
| Acinar Cell Carcinoma of the Pancreas (JHU, J Pathol 2014) paac_jhu_2014 | Pancreatic Acinar Cell Carcinoma | Ssm | 4 | 23 | 17.4% | 4 | cbioportal |
| Melanoma (Broad/Dana Farber, Nature 2012) skcm_broad_dfarber | Cutaneous Melanoma | Ssm | 4 | 26 | 15.4% | 194 | cbioportal |
| Esophageal Adenocarcinoma (DFCI, Nat Genet 2013) esca_broad | Esophageal Adenocarcinoma | Ssm | 8 | 151 | 5.3% | 198 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.