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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
436 cases with simple somatic mutation data · 440 cases total · 2026-06-04 · mapped to Gastric Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 |
| TTN |
| Ssm |
| 235 |
| 436 |
| 53.9% |
| cbioportal |
| 2 | TP53 | Ssm | 213 | 436 | 48.9% | cbioportal |
| 3 | MUC16 | Ssm | 146 | 436 | 33.5% | cbioportal |
| 4 | LRP1B | Ssm | 120 | 436 | 27.5% | cbioportal |
| 5 | SYNE1 | Ssm | 111 | 436 | 25.5% | cbioportal |
| 6 | ARID1A | Ssm | 110 | 436 | 25.2% | cbioportal |
| 7 | CSMD3 | Ssm | 107 | 436 | 24.5% | cbioportal |
| 8 | FLG | Ssm | 103 | 436 | 23.6% | cbioportal |
| 9 | FAT4 | Ssm | 94 | 436 | 21.6% | cbioportal |
| 11 | PCLO | Ssm | 88 | 436 | 20.2% | cbioportal |
| 10 | CSMD1 | Ssm | 88 | 436 | 20.2% | cbioportal |
| 12 | HMCN1 | Ssm | 86 | 436 | 19.7% | cbioportal |
| 13 | OBSCN | Ssm | 81 | 436 | 18.6% | cbioportal |
| 14 | DNAH5 | Ssm | 80 | 436 | 18.3% | cbioportal |
| 15 | RYR2 | Ssm | 79 | 436 | 18.1% | cbioportal |
| 16 | ZFHX4 | Ssm | 79 | 436 | 18.1% | cbioportal |
| 17 | FAT3 | Ssm | 77 | 436 | 17.7% | cbioportal |
| 18 | SPTA1 | Ssm | 77 | 436 | 17.7% | cbioportal |
| 19 | KMT2D | Ssm | 73 | 436 | 16.7% | cbioportal |
| 20 | PCDH15 | Ssm | 72 | 436 | 16.5% | cbioportal |
| 21 | PIK3CA | Ssm | 71 | 436 | 16.3% | cbioportal |
| 22 | AHNAK2 | Ssm | 68 | 436 | 15.6% | cbioportal |
| 24 | SACS | Ssm | 64 | 436 | 14.7% | cbioportal |
| 23 | PLEC | Ssm | 64 | 436 | 14.7% | cbioportal |
| 25 | COL12A1 | Ssm | 62 | 436 | 14.2% | cbioportal |
| 30 | USH2A | Ssm | 62 | 436 | 14.2% | cbioportal |
| 29 | RYR3 | Ssm | 62 | 436 | 14.2% | cbioportal |
| 28 | LAMA1 | Ssm | 62 | 436 | 14.2% | cbioportal |
| 26 | CUBN | Ssm | 62 | 436 | 14.2% | cbioportal |
| 27 | DNAH11 | Ssm | 62 | 436 | 14.2% | cbioportal |
Data updated 21 days agoSource updated 2026-06-04