Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
346 cases with simple somatic mutation data · 359 cases total · 2026-01-13 · mapped to Cutaneous Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TTN | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 246 |
| 346 |
| 71.1% |
| cbioportal |
| 2 | MUC16 | Ssm | 232 | 346 | 67.1% | cbioportal |
| 3 | PCDHAC2 | Ssm | 184 | 346 | 53.2% | cbioportal |
| 4 | BRAF | Ssm | 177 | 346 | 51.2% | cbioportal |
| 5 | DNAH5 | Ssm | 171 | 346 | 49.4% | cbioportal |
| 6 | PCDHGC5 | Ssm | 164 | 346 | 47.4% | cbioportal |
| 7 | PCLO | Ssm | 150 | 346 | 43.4% | cbioportal |
| 8 | APOB | Ssm | 129 | 346 | 37.3% | cbioportal |
| 9 | LRP1B | Ssm | 125 | 346 | 36.1% | cbioportal |
| 10 | ADGRV1 | Ssm | 123 | 346 | 35.5% | cbioportal |
| 11 | CSMD1 | Ssm | 118 | 346 | 34.1% | cbioportal |
| 12 | RP1 | Ssm | 118 | 346 | 34.1% | cbioportal |
| 13 | FAT3 | Ssm | 117 | 346 | 33.8% | cbioportal |
| 14 | MGAM | Ssm | 116 | 346 | 33.5% | cbioportal |
| 15 | DNAH7 | Ssm | 114 | 346 | 32.9% | cbioportal |
| 16 | XIRP2 | Ssm | 114 | 346 | 32.9% | cbioportal |
| 17 | MUC17 | Ssm | 113 | 346 | 32.7% | cbioportal |
| 18 | ANK3 | Ssm | 111 | 346 | 32.1% | cbioportal |
| 19 | FLG | Ssm | 111 | 346 | 32.1% | cbioportal |
| 20 | DSCAM | Ssm | 108 | 346 | 31.2% | cbioportal |
| 21 | USH2A | Ssm | 108 | 346 | 31.2% | cbioportal |
| 22 | CSMD3 | Ssm | 106 | 346 | 30.6% | cbioportal |
| 23 | PKHD1L1 | Ssm | 105 | 346 | 30.3% | cbioportal |
| 24 | CSMD2 | Ssm | 104 | 346 | 30.1% | cbioportal |
| 25 | DNAH8 | Ssm | 103 | 346 | 29.8% | cbioportal |
| 27 | THSD7B | Ssm | 103 | 346 | 29.8% | cbioportal |
| 26 | DNAH9 | Ssm | 103 | 346 | 29.8% | cbioportal |
| 28 | DNAH3 | Ssm | 102 | 346 | 29.5% | cbioportal |
| 29 | FAT4 | Ssm | 102 | 346 | 29.5% | cbioportal |
| 30 | MXRA5 | Ssm | 100 | 346 | 28.9% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13