Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
232 cases with simple somatic mutation data · 232 cases total · 2026-01-16 · mapped to Lung Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | EGFR |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 66 |
| 232 |
| 28.4% |
| cbioportal |
| 2 | TP53 | Ssm | 36 | 232 | 15.5% | cbioportal |
| 3 | TTN | Ssm | 21 | 232 | 9.1% | cbioportal |
| 5 | RBM10 | Ssm | 17 | 232 | 7.3% | cbioportal |
| 4 | KRAS | Ssm | 17 | 232 | 7.3% | cbioportal |
| 6 | MUC16 | Ssm | 12 | 232 | 5.2% | cbioportal |
| 7 | LRRK2 | Ssm | 10 | 232 | 4.3% | cbioportal |
| 9 | SETD2 | Ssm | 10 | 232 | 4.3% | cbioportal |
| 8 | PIK3CA | Ssm | 10 | 232 | 4.3% | cbioportal |
| 10 | ERBB2 | Ssm | 9 | 232 | 3.9% | cbioportal |
| 11 | HUWE1 | Ssm | 9 | 232 | 3.9% | cbioportal |
| 15 | XIRP2 | Ssm | 9 | 232 | 3.9% | cbioportal |
| 12 | REV3L | Ssm | 9 | 232 | 3.9% | cbioportal |
| 13 | RYR2 | Ssm | 9 | 232 | 3.9% | cbioportal |
| 14 | UBA1 | Ssm | 9 | 232 | 3.9% | cbioportal |
| 16 | ZFHX4 | Ssm | 9 | 232 | 3.9% | cbioportal |
| 17 | BIRC6 | Ssm | 8 | 232 | 3.4% | cbioportal |
| 20 | LRP1B | Ssm | 8 | 232 | 3.4% | cbioportal |
| 19 | CSMD3 | Ssm | 8 | 232 | 3.4% | cbioportal |
| 18 | CSMD1 | Ssm | 8 | 232 | 3.4% | cbioportal |
| 23 | ARID2 | Ssm | 7 | 232 | 3% | cbioportal |
| 27 | GLUD2 | Ssm | 7 | 232 | 3% | cbioportal |
| 28 | MET | Ssm | 7 | 232 | 3% | cbioportal |
| 26 | FSIP2 | Ssm | 7 | 232 | 3% | cbioportal |
| 25 | FBN2 | Ssm | 7 | 232 | 3% | cbioportal |
| 22 | ARID1A | Ssm | 7 | 232 | 3% | cbioportal |
| 21 | AR | Ssm | 7 | 232 | 3% | cbioportal |
| 24 | DNAH5 | Ssm | 7 | 232 | 3% | cbioportal |
| 38 | NF1 | Ssm | 6 | 232 | 2.6% | cbioportal |
| 31 | APOB | Ssm | 6 | 232 | 2.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16