Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
370 cases with simple somatic mutation data · 379 cases total · 2026-01-13 · mapped to Hepatocellular Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 107 |
| 370 |
| 28.9% |
| cbioportal |
| 2 | CTNNB1 | Ssm | 95 | 370 | 25.7% | cbioportal |
| 3 | TTN | Ssm | 90 | 370 | 24.3% | cbioportal |
| 4 | MUC16 | Ssm | 59 | 370 | 15.9% | cbioportal |
| 5 | ALB | Ssm | 48 | 370 | 13% | cbioportal |
| 6 | PCLO | Ssm | 42 | 370 | 11.4% | cbioportal |
| 7 | RYR2 | Ssm | 34 | 370 | 9.2% | cbioportal |
| 8 | LRP1B | Ssm | 32 | 370 | 8.6% | cbioportal |
| 9 | APOB | Ssm | 31 | 370 | 8.4% | cbioportal |
| 10 | CSMD3 | Ssm | 29 | 370 | 7.8% | cbioportal |
| 11 | XIRP2 | Ssm | 29 | 370 | 7.8% | cbioportal |
| 13 | OBSCN | Ssm | 28 | 370 | 7.6% | cbioportal |
| 12 | ARID1A | Ssm | 28 | 370 | 7.6% | cbioportal |
| 14 | ABCA13 | Ssm | 27 | 370 | 7.3% | cbioportal |
| 15 | FLG | Ssm | 27 | 370 | 7.3% | cbioportal |
| 16 | AXIN1 | Ssm | 26 | 370 | 7% | cbioportal |
| 17 | HMCN1 | Ssm | 26 | 370 | 7% | cbioportal |
| 18 | CACNA1E | Ssm | 25 | 370 | 6.8% | cbioportal |
| 21 | USH2A | Ssm | 24 | 370 | 6.5% | cbioportal |
| 20 | SPTA1 | Ssm | 24 | 370 | 6.5% | cbioportal |
| 19 | CUBN | Ssm | 24 | 370 | 6.5% | cbioportal |
| 22 | ADGRV1 | Ssm | 23 | 370 | 6.2% | cbioportal |
| 24 | DOCK2 | Ssm | 23 | 370 | 6.2% | cbioportal |
| 23 | DNAH7 | Ssm | 23 | 370 | 6.2% | cbioportal |
| 25 | RYR1 | Ssm | 22 | 370 | 5.9% | cbioportal |
| 29 | FAT3 | Ssm | 21 | 370 | 5.7% | cbioportal |
| 30 | PRKDC | Ssm | 21 | 370 | 5.7% | cbioportal |
| 28 | DMD | Ssm | 21 | 370 | 5.7% | cbioportal |
| 27 | CSMD1 | Ssm | 21 | 370 | 5.7% | cbioportal |
| 26 | COL11A1 | Ssm | 21 | 370 | 5.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13