Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
410 cases with simple somatic mutation data · 411 cases total · 2026-08-20 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | TP53 | Ssm | 202 | 410 | 49.3% | cbioportal |
| 2 | TTN | Ssm | 192 | 410 | 46.8% | cbioportal |
| 3 | MUC16 | Ssm | 119 | 410 | 29% | cbioportal |
| 4 | KMT2D | Ssm | 117 | 410 | 28.5% | cbioportal |
| 5 | KDM6A | Ssm | 106 | 410 | 25.9% | cbioportal |
| 6 | ARID1A | Ssm | 105 | 410 | 25.6% | cbioportal |
| 7 | PIK3CA | Ssm | 90 | 410 | 22% | cbioportal |
| 8 | SYNE1 | Ssm | 87 | 410 | 21.2% | cbioportal |
| 9 | KMT2C | Ssm | 81 | 410 | 19.8% | cbioportal |
| 10 | RB1 | Ssm | 78 | 410 | 19% | cbioportal |
| 12 | RYR2 | Ssm | 76 | 410 | 18.5% | cbioportal |
| 11 | MACF1 | Ssm | 76 | 410 | 18.5% | cbioportal |
| 13 | HMCN1 | Ssm | 75 | 410 | 18.3% | cbioportal |
| 14 | FLG | Ssm | 68 | 410 | 16.6% | cbioportal |
| 16 | FAT4 | Ssm | 63 | 410 | 15.4% | cbioportal |
| 15 | EP300 | Ssm | 63 | 410 | 15.4% | cbioportal |
| 17 | FGFR3 | Ssm | 59 | 410 | 14.4% | cbioportal |
| 18 | CSMD3 | Ssm | 58 | 410 | 14.1% | cbioportal |
| 19 | STAG2 | Ssm | 57 | 410 | 13.9% | cbioportal |
| 20 | ATM | Ssm | 55 | 410 | 13.4% | cbioportal |
| 23 | OBSCN | Ssm | 54 | 410 | 13.2% | cbioportal |
| 22 | ELF3 | Ssm | 54 | 410 | 13.2% | cbioportal |
| 21 | BIRC6 | Ssm | 54 | 410 | 13.2% | cbioportal |
| 24 | CUBN | Ssm | 53 | 410 | 12.9% | cbioportal |
| 25 | NEB | Ssm | 53 | 410 | 12.9% | cbioportal |
| 28 | SYNE2 | Ssm | 52 | 410 | 12.7% | cbioportal |
| 26 | DNAH11 | Ssm | 52 | 410 | 12.7% | cbioportal |
| 27 | LRP1B | Ssm | 52 | 410 | 12.7% | cbioportal |
| 30 | CREBBP | Ssm | 51 | 410 | 12.4% | cbioportal |
| 31 | DNAH5 | Ssm | 51 | 410 | 12.4% | cbioportal |
Data updated 21 days agoSource updated 2026-08-20