Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
120 cases with simple somatic mutation data · 120 cases total · 2026-03-04 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm | 31 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 120 |
| 25.8% |
| cbioportal |
| 2 | BRCA2 | Ssm | 22 | 120 | 18.3% | cbioportal |
| 3 | ZFHX3 | Ssm | 15 | 116 | 12.9% | cbioportal |
| 4 | FOXA1 | Ssm | 14 | 120 | 11.7% | cbioportal |
| 5 | KMT2C | Ssm | 14 | 120 | 11.7% | cbioportal |
| 6 | CDK12 | Ssm | 12 | 120 | 10% | cbioportal |
| 7 | ATM | Ssm | 10 | 120 | 8.3% | cbioportal |
| 8 | KMT2D | Ssm | 9 | 120 | 7.5% | cbioportal |
| 9 | SPOP | Ssm | 9 | 120 | 7.5% | cbioportal |
| 10 | SPEN | Ssm | 8 | 120 | 6.7% | cbioportal |
| 14 | MGA | Ssm | 7 | 116 | 6% | cbioportal |
| 12 | AR | Ssm | 7 | 120 | 5.8% | cbioportal |
| 13 | BRCA1 | Ssm | 7 | 120 | 5.8% | cbioportal |
| 11 | APC | Ssm | 7 | 120 | 5.8% | cbioportal |
| 27 | TP53BP1 | Ssm | 5 | 90 | 5.6% | cbioportal |
| 19 | PTEN | Ssm | 6 | 120 | 5% | cbioportal |
| 15 | CTNNB1 | Ssm | 6 | 120 | 5% | cbioportal |
| 20 | PTPRD | Ssm | 6 | 120 | 5% | cbioportal |
| 18 | PTCH1 | Ssm | 6 | 120 | 5% | cbioportal |
| 17 | NCOR1 | Ssm | 6 | 120 | 5% | cbioportal |
| 16 | KMT2A | Ssm | 6 | 120 | 5% | cbioportal |
| 184 | GNB1 | Ssm | 1 | 22 | 4.5% | cbioportal |
| 150 | ARHGAP35 | Ssm | 1 | 22 | 4.5% | cbioportal |
| 31 | CARM1 | Ssm | 4 | 90 | 4.4% | cbioportal |
| 35 | ERF | Ssm | 4 | 90 | 4.4% | cbioportal |
| 21 | ANKRD11 | Ssm | 5 | 116 | 4.3% | cbioportal |
| 23 | MED12 | Ssm | 5 | 120 | 4.2% | cbioportal |
| 25 | SETD2 | Ssm | 5 | 120 | 4.2% | cbioportal |
| 26 | SMARCA4 | Ssm | 5 | 120 | 4.2% | cbioportal |
| 22 | KDM6A | Ssm | 5 | 120 | 4.2% | cbioportal |
Data updated 21 days agoSource updated 2026-03-04