Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
514 cases with simple somatic mutation data · 514 cases total · 2026-06-03 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 |
| IDH1 |
| Ssm |
| 395 |
| 514 |
| 76.8% |
| cbioportal |
| 2 | TP53 | Ssm | 249 | 514 | 48.4% | cbioportal |
| 3 | ATRX | Ssm | 194 | 514 | 37.7% | cbioportal |
| 4 | CIC | Ssm | 108 | 514 | 21% | cbioportal |
| 5 | TTN | Ssm | 62 | 514 | 12.1% | cbioportal |
| 6 | FUBP1 | Ssm | 48 | 514 | 9.3% | cbioportal |
| 7 | PIK3CA | Ssm | 42 | 514 | 8.2% | cbioportal |
| 8 | NOTCH1 | Ssm | 38 | 514 | 7.4% | cbioportal |
| 9 | MUC16 | Ssm | 36 | 514 | 7% | cbioportal |
| 10 | EGFR | Ssm | 35 | 514 | 6.8% | cbioportal |
| 11 | NF1 | Ssm | 31 | 514 | 6% | cbioportal |
| 12 | SMARCA4 | Ssm | 25 | 514 | 4.9% | cbioportal |
| 13 | PTEN | Ssm | 24 | 514 | 4.7% | cbioportal |
| 14 | FLG | Ssm | 23 | 514 | 4.5% | cbioportal |
| 15 | PIK3R1 | Ssm | 22 | 514 | 4.3% | cbioportal |
| 16 | IDH2 | Ssm | 21 | 514 | 4.1% | cbioportal |
| 17 | RYR2 | Ssm | 21 | 514 | 4.1% | cbioportal |
| 18 | ZBTB20 | Ssm | 20 | 514 | 3.9% | cbioportal |
| 19 | ARID1A | Ssm | 19 | 514 | 3.7% | cbioportal |
| 20 | NIPBL | Ssm | 18 | 514 | 3.5% | cbioportal |
| 21 | OBSCN | Ssm | 18 | 514 | 3.5% | cbioportal |
| 22 | PCLO | Ssm | 18 | 514 | 3.5% | cbioportal |
| 23 | HMCN1 | Ssm | 17 | 514 | 3.3% | cbioportal |
| 24 | MUC17 | Ssm | 16 | 514 | 3.1% | cbioportal |
| 25 | APOB | Ssm | 15 | 514 | 2.9% | cbioportal |
| 27 | LRP2 | Ssm | 15 | 514 | 2.9% | cbioportal |
| 26 | BCOR | Ssm | 15 | 514 | 2.9% | cbioportal |
| 29 | TCF12 | Ssm | 14 | 514 | 2.7% | cbioportal |
| 28 | ADGRV1 | Ssm | 14 | 514 | 2.7% | cbioportal |
| 30 | FAT2 | Ssm | 13 | 514 | 2.5% | cbioportal |
Data updated 21 days agoSource updated 2026-06-03