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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
405 cases with simple somatic mutation data · 604 cases total · 2026-01-13 · mapped to High-Grade Serous Ovarian Cancer EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 369 |
| 405 |
| 91.1% |
| cbioportal |
| 2 | TTN | Ssm | 96 | 405 | 23.7% | cbioportal |
| 3 | CSMD3 | Ssm | 36 | 405 | 8.9% | cbioportal |
| 4 | USH2A | Ssm | 31 | 405 | 7.7% | cbioportal |
| 5 | NF1 | Ssm | 29 | 405 | 7.2% | cbioportal |
| 6 | RYR2 | Ssm | 28 | 405 | 6.9% | cbioportal |
| 7 | HMCN1 | Ssm | 26 | 405 | 6.4% | cbioportal |
| 8 | MUC16 | Ssm | 26 | 405 | 6.4% | cbioportal |
| 9 | FAT3 | Ssm | 23 | 405 | 5.7% | cbioportal |
| 11 | SI | Ssm | 22 | 405 | 5.4% | cbioportal |
| 10 | MACF1 | Ssm | 22 | 405 | 5.4% | cbioportal |
| 14 | FLG2 | Ssm | 21 | 405 | 5.2% | cbioportal |
| 12 | AHNAK | Ssm | 21 | 405 | 5.2% | cbioportal |
| 13 | APOB | Ssm | 21 | 405 | 5.2% | cbioportal |
| 15 | MUC17 | Ssm | 21 | 405 | 5.2% | cbioportal |
| 19 | LRP1B | Ssm | 20 | 405 | 4.9% | cbioportal |
| 17 | DNAH3 | Ssm | 20 | 405 | 4.9% | cbioportal |
| 18 | FLG | Ssm | 20 | 405 | 4.9% | cbioportal |
| 16 | CDK12 | Ssm | 20 | 405 | 4.9% | cbioportal |
| 20 | BRCA1 | Ssm | 19 | 405 | 4.7% | cbioportal |
| 21 | DNAH5 | Ssm | 19 | 405 | 4.7% | cbioportal |
| 23 | LRP1 | Ssm | 19 | 405 | 4.7% | cbioportal |
| 22 | DST | Ssm | 19 | 405 | 4.7% | cbioportal |
| 27 | SYNE2 | Ssm | 18 | 405 | 4.4% | cbioportal |
| 25 | FCGBP | Ssm | 18 | 405 | 4.4% | cbioportal |
| 28 | TG | Ssm | 18 | 405 | 4.4% | cbioportal |
| 26 | SYNE1 | Ssm | 18 | 405 | 4.4% | cbioportal |
| 24 | COL6A3 | Ssm | 18 | 405 | 4.4% | cbioportal |
| 33 | RELN | Ssm | 17 | 405 | 4.2% | cbioportal |
| 34 | TOP2A | Ssm | 17 | 405 | 4.2% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13