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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
200 cases with simple somatic mutation data · 200 cases total · 2026-06-05 · mapped to Acute Myeloid Leukemia EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 |
| FLT3 |
| Ssm |
| 59 |
| 200 |
| 29.5% |
| cbioportal |
| 2 | NPM1 | Ssm | 54 | 200 | 27% | cbioportal |
| 3 | DNMT3A | Ssm | 50 | 200 | 25% | cbioportal |
| 4 | IDH2 | Ssm | 21 | 200 | 10.5% | cbioportal |
| 5 | IDH1 | Ssm | 19 | 200 | 9.5% | cbioportal |
| 6 | RUNX1 | Ssm | 19 | 200 | 9.5% | cbioportal |
| 7 | TET2 | Ssm | 17 | 200 | 8.5% | cbioportal |
| 9 | TP53 | Ssm | 16 | 200 | 8% | cbioportal |
| 8 | NRAS | Ssm | 16 | 200 | 8% | cbioportal |
| 10 | TTN | Ssm | 14 | 200 | 7% | cbioportal |
| 11 | CEBPA | Ssm | 13 | 200 | 6.5% | cbioportal |
| 12 | WT1 | Ssm | 13 | 200 | 6.5% | cbioportal |
| 13 | BPIFC | Ssm | 11 | 200 | 5.5% | cbioportal |
| 14 | KRAS | Ssm | 10 | 200 | 5% | cbioportal |
| 15 | PTPN11 | Ssm | 10 | 200 | 5% | cbioportal |
| 16 | SMC1A | Ssm | 9 | 200 | 4.5% | cbioportal |
| 19 | U2AF1 | Ssm | 8 | 200 | 4% | cbioportal |
| 18 | MUC16 | Ssm | 8 | 200 | 4% | cbioportal |
| 17 | KIT | Ssm | 8 | 200 | 4% | cbioportal |
| 24 | SMC3 | Ssm | 7 | 200 | 3.5% | cbioportal |
| 20 | ASXL1 | Ssm | 7 | 200 | 3.5% | cbioportal |
| 23 | SENP6 | Ssm | 7 | 200 | 3.5% | cbioportal |
| 21 | HPS3 | Ssm | 7 | 200 | 3.5% | cbioportal |
| 22 | PHF6 | Ssm | 7 | 200 | 3.5% | cbioportal |
| 26 | BRWD1 | Ssm | 6 | 200 | 3% | cbioportal |
| 31 | GDI2 | Ssm | 6 | 200 | 3% | cbioportal |
| 30 | GABRG3 | Ssm | 6 | 200 | 3% | cbioportal |
| 29 | FREM2 | Ssm | 6 | 200 | 3% | cbioportal |
| 28 | DNAH11 | Ssm | 6 | 200 | 3% | cbioportal |
| 27 | CSMD1 | Ssm | 6 | 200 | 3% | cbioportal |
Data updated 21 days agoSource updated 2026-06-05