Other
Neoplasm by Site
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Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
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Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
174 cases with simple somatic mutation data · 200 cases total · Data Release 46.0 · mapped to Malignant Breast Neoplasm CURATED_BROADER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | TP53 | Ssm | 58 | 174 | 33.3% | gdc |
| 2 | PIK3CA | Ssm | 52 | 174 | 29.9% | gdc |
| 3 | TTN | Ssm | 28 | 174 | 16.1% | gdc |
| 4 | CDH1 | Ssm | 22 | 174 | 12.6% | gdc |
| 5 | GATA3 | Ssm | 20 | 174 | 11.5% | gdc |
| 6 | HMCN1 | Ssm | 16 | 174 | 9.2% | gdc |
| 7 | MUC16 | Ssm | 13 | 174 | 7.5% | gdc |
| 8 | PTEN | Ssm | 12 | 174 | 6.9% | gdc |
| 10 | RYR1 | Ssm | 11 | 174 | 6.3% | gdc |
| 9 | TENM2 | Ssm | 11 | 174 | 6.3% | gdc |
| 13 | USH2A | Ssm | 10 | 174 | 5.7% | gdc |
| 14 | MUC5B | Ssm | 10 | 174 | 5.7% | gdc |
| 16 | NF1 | Ssm | 10 | 174 | 5.7% | gdc |
| 11 | DYNC1H1 | Ssm | 10 | 174 | 5.7% | gdc |
| 17 | RYR2 | Ssm | 10 | 174 | 5.7% | gdc |
| 12 | RIMS2 | Ssm | 10 | 174 | 5.7% | gdc |
| 15 | RELN | Ssm | 10 | 174 | 5.7% | gdc |
| 20 | ASTN1 | Ssm | 9 | 174 | 5.2% | gdc |
| 18 | CUBN | Ssm | 9 | 174 | 5.2% | gdc |
| 21 | ARID1A | Ssm | 9 | 174 | 5.2% | gdc |
| 19 | MAP2K4 | Ssm | 9 | 174 | 5.2% | gdc |
| 25 | ZFHX4 | Ssm | 8 | 174 | 4.6% | gdc |
| 31 | DNAH5 | Ssm | 8 | 174 | 4.6% | gdc |
| 22 | DST | Ssm | 8 | 174 | 4.6% | gdc |
| 27 | TBX3 | Ssm | 8 | 174 | 4.6% | gdc |
| 23 | CACNA1H | Ssm | 8 | 174 | 4.6% | gdc |
| 28 | KIAA1109 | Ssm | 8 | 174 | 4.6% | gdc |
| 30 | HERC2 | Ssm | 8 | 174 | 4.6% | gdc |
| 24 | GVINP1 | Ssm | 8 | 174 | 4.6% | gdc |
| 29 | KMT2C | Ssm | 8 | 174 | 4.6% | gdc |
Data updated 22 days agoSource updated Data Release 46.0