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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
22 cases with simple somatic mutation data · 22 cases total · 2026-01-06 · mapped to Colorectal Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 22 |
| 22 |
| 100% |
| cbioportal |
| 3 | TP53 | Ssm | 21 | 22 | 95.5% | cbioportal |
| 2 | APC | Ssm | 21 | 22 | 95.5% | cbioportal |
| 7 | USP8 | Ssm | 13 | 19 | 68.4% | cbioportal |
| 4 | SMAD4 | Ssm | 14 | 22 | 63.6% | cbioportal |
| 9 | HLA-C | Ssm | 12 | 19 | 63.2% | cbioportal |
| 6 | PDCD1 | Ssm | 13 | 22 | 59.1% | cbioportal |
| 5 | ATM | Ssm | 13 | 22 | 59.1% | cbioportal |
| 11 | PIK3C2G | Ssm | 12 | 22 | 54.5% | cbioportal |
| 8 | ABRAXAS1 | Ssm | 12 | 22 | 54.5% | cbioportal |
| 10 | MGA | Ssm | 12 | 22 | 54.5% | cbioportal |
| 12 | TET2 | Ssm | 12 | 22 | 54.5% | cbioportal |
| 15 | ZFHX3 | Ssm | 11 | 22 | 50% | cbioportal |
| 14 | TCF7L2 | Ssm | 11 | 22 | 50% | cbioportal |
| 13 | HLA-A | Ssm | 11 | 22 | 50% | cbioportal |
| 42 | GAB1 | Ssm | 9 | 19 | 47.4% | cbioportal |
| 50 | SETDB1 | Ssm | 9 | 19 | 47.4% | cbioportal |
| 32 | SOX17 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 20 | FANCA | Ssm | 10 | 22 | 45.5% | cbioportal |
| 17 | AMER1 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 29 | PRKN | Ssm | 10 | 22 | 45.5% | cbioportal |
| 21 | IGF1 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 31 | SDHD | Ssm | 10 | 22 | 45.5% | cbioportal |
| 22 | JAK1 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 30 | RAD54L | Ssm | 10 | 22 | 45.5% | cbioportal |
| 28 | NSD1 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 23 | KMT2D | Ssm | 10 | 22 | 45.5% | cbioportal |
| 33 | STAT3 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 27 | NEGR1 | Ssm | 10 | 22 | 45.5% | cbioportal |
| 26 | MYCN | Ssm | 10 | 22 | 45.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-06