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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
64 cases with simple somatic mutation data · 64 cases total · 2026-01-13 · mapped to Cutaneous Melanoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | MUC16 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 49 |
| 64 |
| 76.6% |
| cbioportal |
| 2 | TTN | Ssm | 48 | 64 | 75% | cbioportal |
| 3 | DNAH5 | Ssm | 36 | 64 | 56.3% | cbioportal |
| 4 | PCLO | Ssm | 33 | 64 | 51.6% | cbioportal |
| 5 | FAT4 | Ssm | 32 | 64 | 50% | cbioportal |
| 6 | BRAF | Ssm | 30 | 64 | 46.9% | cbioportal |
| 7 | RP1 | Ssm | 28 | 64 | 43.8% | cbioportal |
| 11 | XIRP2 | Ssm | 26 | 64 | 40.6% | cbioportal |
| 9 | CSMD1 | Ssm | 26 | 64 | 40.6% | cbioportal |
| 8 | ADGRV1 | Ssm | 26 | 64 | 40.6% | cbioportal |
| 10 | LRP1B | Ssm | 26 | 64 | 40.6% | cbioportal |
| 13 | HYDIN | Ssm | 25 | 64 | 39.1% | cbioportal |
| 12 | DNAH7 | Ssm | 25 | 64 | 39.1% | cbioportal |
| 14 | PKHD1L1 | Ssm | 25 | 64 | 39.1% | cbioportal |
| 15 | DCC | Ssm | 24 | 64 | 37.5% | cbioportal |
| 19 | USH2A | Ssm | 23 | 64 | 35.9% | cbioportal |
| 16 | CSMD3 | Ssm | 23 | 64 | 35.9% | cbioportal |
| 17 | DNAH8 | Ssm | 23 | 64 | 35.9% | cbioportal |
| 18 | OBSCN | Ssm | 23 | 64 | 35.9% | cbioportal |
| 21 | APOB | Ssm | 22 | 64 | 34.4% | cbioportal |
| 20 | ANK3 | Ssm | 22 | 64 | 34.4% | cbioportal |
| 22 | PCDH15 | Ssm | 22 | 64 | 34.4% | cbioportal |
| 23 | CSMD2 | Ssm | 21 | 64 | 32.8% | cbioportal |
| 27 | SCN10A | Ssm | 20 | 64 | 31.3% | cbioportal |
| 26 | NPAP1 | Ssm | 20 | 64 | 31.3% | cbioportal |
| 30 | ZNF804A | Ssm | 20 | 64 | 31.3% | cbioportal |
| 29 | UNC13C | Ssm | 20 | 64 | 31.3% | cbioportal |
| 25 | FMN2 | Ssm | 20 | 64 | 31.3% | cbioportal |
| 28 | THSD7B | Ssm | 20 | 64 | 31.3% | cbioportal |
| 24 | DSCAM | Ssm | 20 | 64 | 31.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13