Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
444 cases with simple somatic mutation data · 444 cases total · 2026-01-07 · mapped to Diffuse Glioma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 206 |
| 444 |
| 46.4% |
| cbioportal |
| 2 | IDH1 | Ssm | 174 | 444 | 39.2% | cbioportal |
| 3 | TTN | Ssm | 109 | 444 | 24.5% | cbioportal |
| 4 | ATRX | Ssm | 103 | 444 | 23.2% | cbioportal |
| 5 | PTEN | Ssm | 101 | 444 | 22.7% | cbioportal |
| 6 | EGFR | Ssm | 83 | 444 | 18.7% | cbioportal |
| 7 | MUC16 | Ssm | 80 | 444 | 18% | cbioportal |
| 8 | NF1 | Ssm | 71 | 444 | 16% | cbioportal |
| 9 | RYR2 | Ssm | 59 | 444 | 13.3% | cbioportal |
| 10 | OBSCN | Ssm | 57 | 444 | 12.8% | cbioportal |
| 11 | FLG | Ssm | 53 | 444 | 11.9% | cbioportal |
| 12 | PKHD1 | Ssm | 51 | 444 | 11.5% | cbioportal |
| 13 | PIK3CA | Ssm | 50 | 444 | 11.3% | cbioportal |
| 14 | ADGRV1 | Ssm | 48 | 444 | 10.8% | cbioportal |
| 15 | MUC17 | Ssm | 48 | 444 | 10.8% | cbioportal |
| 18 | LRP2 | Ssm | 44 | 444 | 9.9% | cbioportal |
| 17 | HMCN1 | Ssm | 44 | 444 | 9.9% | cbioportal |
| 16 | CIC | Ssm | 44 | 444 | 9.9% | cbioportal |
| 19 | DNAH11 | Ssm | 43 | 444 | 9.7% | cbioportal |
| 20 | DNAH5 | Ssm | 42 | 444 | 9.5% | cbioportal |
| 22 | CSMD3 | Ssm | 41 | 444 | 9.2% | cbioportal |
| 21 | AHNAK2 | Ssm | 41 | 444 | 9.2% | cbioportal |
| 23 | MUC12 | Ssm | 41 | 444 | 9.2% | cbioportal |
| 24 | NEB | Ssm | 41 | 444 | 9.2% | cbioportal |
| 25 | SYNE1 | Ssm | 40 | 444 | 9% | cbioportal |
| 26 | MUC5B | Ssm | 39 | 444 | 8.8% | cbioportal |
| 28 | USH2A | Ssm | 38 | 444 | 8.6% | cbioportal |
| 27 | PCLO | Ssm | 38 | 444 | 8.6% | cbioportal |
| 29 | AHNAK | Ssm | 37 | 444 | 8.3% | cbioportal |
| 30 | RB1 | Ssm | 36 | 444 | 8.1% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07