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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
276 cases with simple somatic mutation data · 283 cases total · 2026-06-05 · mapped to Papillary Renal Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 1 | TTN | Ssm | 51 | 276 | 18.5% | cbioportal |
| 2 | MUC16 | Ssm | 27 | 276 | 9.8% | cbioportal |
| 3 | MET | Ssm | 22 | 276 | 8% | cbioportal |
| 5 | KMT2C | Ssm | 19 | 276 | 6.9% | cbioportal |
| 4 | BLTP1 | Ssm | 19 | 276 | 6.9% | cbioportal |
| 7 | OBSCN | Ssm | 18 | 276 | 6.5% | cbioportal |
| 6 | KMT2D | Ssm | 18 | 276 | 6.5% | cbioportal |
| 8 | PKHD1 | Ssm | 18 | 276 | 6.5% | cbioportal |
| 10 | SETD2 | Ssm | 17 | 276 | 6.2% | cbioportal |
| 9 | MACF1 | Ssm | 17 | 276 | 6.2% | cbioportal |
| 11 | FAT1 | Ssm | 16 | 276 | 5.8% | cbioportal |
| 12 | USH2A | Ssm | 15 | 276 | 5.4% | cbioportal |
| 13 | BAP1 | Ssm | 14 | 276 | 5.1% | cbioportal |
| 14 | DNAH8 | Ssm | 14 | 276 | 5.1% | cbioportal |
| 15 | WDFY3 | Ssm | 14 | 276 | 5.1% | cbioportal |
| 20 | SRRM2 | Ssm | 13 | 276 | 4.7% | cbioportal |
| 19 | HUWE1 | Ssm | 13 | 276 | 4.7% | cbioportal |
| 22 | UBR4 | Ssm | 13 | 276 | 4.7% | cbioportal |
| 21 | SYNE1 | Ssm | 13 | 276 | 4.7% | cbioportal |
| 17 | DNAH1 | Ssm | 13 | 276 | 4.7% | cbioportal |
| 16 | CUBN | Ssm | 13 | 276 | 4.7% | cbioportal |
| 18 | HERC2 | Ssm | 13 | 276 | 4.7% | cbioportal |
| 30 | SYNE2 | Ssm | 12 | 276 | 4.3% | cbioportal |
| 29 | PBRM1 | Ssm | 12 | 276 | 4.3% | cbioportal |
| 27 | MDN1 | Ssm | 12 | 276 | 4.3% | cbioportal |
| 28 | NEB | Ssm | 12 | 276 | 4.3% | cbioportal |
| 26 | DST | Ssm | 12 | 276 | 4.3% | cbioportal |
| 25 | CENPF | Ssm | 12 | 276 | 4.3% | cbioportal |
| 23 | ARID1A | Ssm | 12 | 276 | 4.3% | cbioportal |
| 24 | BIRC6 | Ssm | 12 | 276 | 4.3% | cbioportal |
Data updated 21 days agoSource updated 2026-06-05