Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
412 cases with simple somatic mutation data · 412 cases total · 2026-01-28 · mapped to Pancreatic Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | KRAS |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 168 |
| 412 |
| 40.8% |
| cbioportal |
| 2 | TP53 | Ssm | 149 | 412 | 36.2% | cbioportal |
| 3 | CDKN2A | Ssm | 37 | 412 | 9% | cbioportal |
| 4 | SMAD4 | Ssm | 34 | 412 | 8.3% | cbioportal |
| 5 | ARID1A | Ssm | 24 | 412 | 5.8% | cbioportal |
| 6 | ATM | Ssm | 23 | 412 | 5.6% | cbioportal |
| 8 | KDM6A | Ssm | 9 | 412 | 2.2% | cbioportal |
| 7 | GNAS | Ssm | 9 | 412 | 2.2% | cbioportal |
| 9 | SF3B1 | Ssm | 9 | 412 | 2.2% | cbioportal |
| 10 | SMARCA4 | Ssm | 8 | 412 | 1.9% | cbioportal |
| 11 | BRCA2 | Ssm | 7 | 412 | 1.7% | cbioportal |
| 12 | FOXO1 | Ssm | 7 | 412 | 1.7% | cbioportal |
| 15 | PTCH1 | Ssm | 7 | 412 | 1.7% | cbioportal |
| 14 | NTRK2 | Ssm | 7 | 412 | 1.7% | cbioportal |
| 13 | NF1 | Ssm | 7 | 412 | 1.7% | cbioportal |
| 16 | APC | Ssm | 6 | 412 | 1.5% | cbioportal |
| 17 | PTEN | Ssm | 6 | 412 | 1.5% | cbioportal |
| 19 | TSC2 | Ssm | 5 | 412 | 1.2% | cbioportal |
| 18 | FBXW7 | Ssm | 5 | 412 | 1.2% | cbioportal |
| 24 | STK11 | Ssm | 4 | 412 | 1% | cbioportal |
| 22 | MSH6 | Ssm | 4 | 412 | 1% | cbioportal |
| 25 | TSC1 | Ssm | 4 | 412 | 1% | cbioportal |
| 20 | CTNNB1 | Ssm | 4 | 412 | 1% | cbioportal |
| 21 | KEAP1 | Ssm | 4 | 412 | 1% | cbioportal |
| 26 | U2AF1 | Ssm | 4 | 412 | 1% | cbioportal |
| 23 | NTRK1 | Ssm | 4 | 412 | 1% | cbioportal |
| 30 | RB1 | Ssm | 3 | 412 | 0.7% | cbioportal |
| 28 | FGFR2 | Ssm | 3 | 412 | 0.7% | cbioportal |
| 29 | PIK3CA | Ssm | 3 | 412 | 0.7% | cbioportal |
| 27 | AKT1 | Ssm | 3 | 412 | 0.7% | cbioportal |
Data updated 21 days agoSource updated 2026-01-28