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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
32 cases with simple somatic mutation data · 32 cases total · 2026-01-07 · mapped to Head and Neck Squamous Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 22 |
| 32 |
| 68.8% |
| cbioportal |
| 2 | NOTCH1 | Ssm | 4 | 32 | 12.5% | cbioportal |
| 3 | RELN | Ssm | 4 | 32 | 12.5% | cbioportal |
| 4 | SYNE1 | Ssm | 4 | 32 | 12.5% | cbioportal |
| 8 | PIK3AP1 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 11 | SI | Ssm | 3 | 32 | 9.4% | cbioportal |
| 5 | EPHA7 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 9 | PIK3CA | Ssm | 3 | 32 | 9.4% | cbioportal |
| 6 | FLG | Ssm | 3 | 32 | 9.4% | cbioportal |
| 10 | RIMBP2 | Ssm | 3 | 32 | 9.4% | cbioportal |
| 7 | HRAS | Ssm | 3 | 32 | 9.4% | cbioportal |
| 23 | GALNT14 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 24 | GRID1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 25 | INSC | Ssm | 2 | 32 | 6.3% | cbioportal |
| 26 | LAMA1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 27 | LRP1B | Ssm | 2 | 32 | 6.3% | cbioportal |
| 28 | MAMDC4 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 29 | MICAL2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 30 | MMP16 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 31 | NCOR1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 32 | NLRP12 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 33 | NRXN2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 34 | NRXN3 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 35 | PCDH15 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 36 | PCDHB2 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 37 | PEAK1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 38 | PKD1L1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 39 | PLCB1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 40 | RASA1 | Ssm | 2 | 32 | 6.3% | cbioportal |
| 41 | SETBP1 | Ssm | 2 | 32 | 6.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07