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CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
64 cases with simple somatic mutation data · 64 cases total · 2026-01-07 · mapped to Gastroesophageal Junction Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 44 |
| 64 |
| 68.8% |
| cbioportal |
| 2 | TTN | Ssm | 27 | 64 | 42.2% | cbioportal |
| 3 | PCLO | Ssm | 17 | 64 | 26.6% | cbioportal |
| 5 | MUC16 | Ssm | 14 | 64 | 21.9% | cbioportal |
| 4 | LRP1B | Ssm | 14 | 64 | 21.9% | cbioportal |
| 6 | SYNE1 | Ssm | 14 | 64 | 21.9% | cbioportal |
| 7 | CDKN2A | Ssm | 12 | 64 | 18.8% | cbioportal |
| 8 | COL4A4 | Ssm | 11 | 64 | 17.2% | cbioportal |
| 10 | CUBN | Ssm | 11 | 64 | 17.2% | cbioportal |
| 9 | CSMD2 | Ssm | 11 | 64 | 17.2% | cbioportal |
| 11 | OBSCN | Ssm | 11 | 64 | 17.2% | cbioportal |
| 12 | CNTNAP4 | Ssm | 10 | 64 | 15.6% | cbioportal |
| 16 | TENM4 | Ssm | 10 | 64 | 15.6% | cbioportal |
| 13 | DNAH5 | Ssm | 10 | 64 | 15.6% | cbioportal |
| 15 | MYO18B | Ssm | 10 | 64 | 15.6% | cbioportal |
| 14 | DNAH8 | Ssm | 10 | 64 | 15.6% | cbioportal |
| 21 | MYH6 | Ssm | 9 | 64 | 14.1% | cbioportal |
| 22 | MYT1L | Ssm | 9 | 64 | 14.1% | cbioportal |
| 19 | CSMD3 | Ssm | 9 | 64 | 14.1% | cbioportal |
| 20 | FLG | Ssm | 9 | 64 | 14.1% | cbioportal |
| 18 | APOB | Ssm | 9 | 64 | 14.1% | cbioportal |
| 17 | ABCA13 | Ssm | 9 | 64 | 14.1% | cbioportal |
| 24 | RYR3 | Ssm | 9 | 64 | 14.1% | cbioportal |
| 23 | RIMS2 | Ssm | 9 | 64 | 14.1% | cbioportal |
| 30 | SDK1 | Ssm | 8 | 64 | 12.5% | cbioportal |
| 31 | TTC6 | Ssm | 8 | 64 | 12.5% | cbioportal |
| 26 | EPHA3 | Ssm | 8 | 64 | 12.5% | cbioportal |
| 27 | FAT4 | Ssm | 8 | 64 | 12.5% | cbioportal |
| 28 | HMCN1 | Ssm | 8 | 64 | 12.5% | cbioportal |
| 29 | PTPRT | Ssm | 8 | 64 | 12.5% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07