Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
1,465 cases with simple somatic mutation data · 1,465 cases total · 2026-01-13 · mapped to Prostate Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 391 |
| 1,465 |
| 26.7% |
| cbioportal |
| 2 | FOXA1 | Ssm | 179 | 1,465 | 12.2% | cbioportal |
| 3 | SPOP | Ssm | 166 | 1,465 | 11.3% | cbioportal |
| 4 | PTEN | Ssm | 97 | 1,465 | 6.6% | cbioportal |
| 5 | KMT2C | Ssm | 89 | 1,465 | 6.1% | cbioportal |
| 6 | CDK12 | Ssm | 88 | 1,465 | 6% | cbioportal |
| 7 | APC | Ssm | 86 | 1,465 | 5.9% | cbioportal |
| 8 | KMT2D | Ssm | 74 | 1,465 | 5.1% | cbioportal |
| 9 | AR | Ssm | 56 | 1,465 | 3.8% | cbioportal |
| 13 | ZFHX3 | Ssm | 51 | 1,337 | 3.8% | cbioportal |
| 10 | CTNNB1 | Ssm | 55 | 1,465 | 3.8% | cbioportal |
| 11 | ATM | Ssm | 52 | 1,465 | 3.5% | cbioportal |
| 12 | PIK3CA | Ssm | 52 | 1,465 | 3.5% | cbioportal |
| 14 | BRCA2 | Ssm | 45 | 1,465 | 3.1% | cbioportal |
| 15 | KDM6A | Ssm | 38 | 1,465 | 2.6% | cbioportal |
| 16 | GRIN2A | Ssm | 36 | 1,465 | 2.5% | cbioportal |
| 17 | MED12 | Ssm | 31 | 1,465 | 2.1% | cbioportal |
| 18 | PTPRD | Ssm | 30 | 1,465 | 2% | cbioportal |
| 19 | SPEN | Ssm | 28 | 1,465 | 1.9% | cbioportal |
| 20 | RB1 | Ssm | 27 | 1,465 | 1.8% | cbioportal |
| 24 | MGA | Ssm | 24 | 1,337 | 1.8% | cbioportal |
| 21 | BRAF | Ssm | 26 | 1,465 | 1.8% | cbioportal |
| 48 | ERF | Ssm | 14 | 809 | 1.7% | cbioportal |
| 22 | PIK3R1 | Ssm | 25 | 1,465 | 1.7% | cbioportal |
| 23 | ASXL1 | Ssm | 24 | 1,465 | 1.6% | cbioportal |
| 25 | NCOR1 | Ssm | 24 | 1,465 | 1.6% | cbioportal |
| 28 | KMT2A | Ssm | 23 | 1,465 | 1.6% | cbioportal |
| 29 | NF1 | Ssm | 23 | 1,465 | 1.6% | cbioportal |
| 27 | JAK1 | Ssm | 23 | 1,465 | 1.6% | cbioportal |
| 26 | ARID1A | Ssm | 23 | 1,465 | 1.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-13