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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
45 cases with simple somatic mutation data · 45 cases total · 2026-01-07 · mapped to High-Grade Serous Ovarian Cancer EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 44 |
| 45 |
| 97.8% |
| cbioportal |
| 2 | BRCA2 | Ssm | 5 | 45 | 11.1% | cbioportal |
| 3 | KMT2D | Ssm | 4 | 45 | 8.9% | cbioportal |
| 9 | AGO2 | Ssm | 2 | 28 | 7.1% | cbioportal |
| 4 | BRCA1 | Ssm | 3 | 45 | 6.7% | cbioportal |
| 8 | NTRK3 | Ssm | 3 | 45 | 6.7% | cbioportal |
| 7 | KMT2C | Ssm | 3 | 45 | 6.7% | cbioportal |
| 6 | KDM5A | Ssm | 3 | 45 | 6.7% | cbioportal |
| 5 | BRD4 | Ssm | 3 | 45 | 6.7% | cbioportal |
| 18 | MGA | Ssm | 2 | 36 | 5.6% | cbioportal |
| 13 | CDK12 | Ssm | 2 | 45 | 4.4% | cbioportal |
| 20 | NCOR1 | Ssm | 2 | 45 | 4.4% | cbioportal |
| 21 | PDGFRA | Ssm | 2 | 45 | 4.4% | cbioportal |
| 22 | PIK3CA | Ssm | 2 | 45 | 4.4% | cbioportal |
| 23 | PIK3R2 | Ssm | 2 | 45 | 4.4% | cbioportal |
| 24 | PPP2R1A | Ssm | 2 | 45 | 4.4% | cbioportal |
| 16 | INPP4B | Ssm | 2 | 45 | 4.4% | cbioportal |
| 11 | AR | Ssm | 2 | 45 | 4.4% | cbioportal |
| 15 | FLT1 | Ssm | 2 | 45 | 4.4% | cbioportal |
| 17 | KIT | Ssm | 2 | 45 | 4.4% | cbioportal |
| 14 | EPHA5 | Ssm | 2 | 45 | 4.4% | cbioportal |
| 12 | ATRX | Ssm | 2 | 45 | 4.4% | cbioportal |
| 10 | APC | Ssm | 2 | 45 | 4.4% | cbioportal |
| 19 | MRE11 | Ssm | 2 | 45 | 4.4% | cbioportal |
| 93 | SESN1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 90 | RRAGC | Ssm | 1 | 28 | 3.6% | cbioportal |
| 61 | INPPL1 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 80 | PRKCI | Ssm | 1 | 28 | 3.6% | cbioportal |
| 79 | PREX2 | Ssm | 1 | 28 | 3.6% | cbioportal |
| 45 | EZH1 | Ssm | 1 | 28 | 3.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-07