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Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
122 cases with simple somatic mutation data · 122 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 51 |
| 122 |
| 41.8% |
| cbioportal |
| 2 | PIK3CA | Ssm | 40 | 122 | 32.8% | cbioportal |
| 3 | TTN | Ssm | 33 | 122 | 27% | cbioportal |
| 4 | MUC16 | Ssm | 15 | 122 | 12.3% | cbioportal |
| 7 | HMCN1 | Ssm | 13 | 122 | 10.7% | cbioportal |
| 6 | AHNAK | Ssm | 13 | 122 | 10.7% | cbioportal |
| 5 | ABCA13 | Ssm | 13 | 122 | 10.7% | cbioportal |
| 8 | OBSCN | Ssm | 13 | 122 | 10.7% | cbioportal |
| 9 | FLG | Ssm | 12 | 122 | 9.8% | cbioportal |
| 12 | RYR1 | Ssm | 11 | 122 | 9% | cbioportal |
| 10 | HERC1 | Ssm | 11 | 122 | 9% | cbioportal |
| 11 | MAP3K1 | Ssm | 11 | 122 | 9% | cbioportal |
| 15 | XIRP2 | Ssm | 10 | 122 | 8.2% | cbioportal |
| 14 | MUC5B | Ssm | 10 | 122 | 8.2% | cbioportal |
| 13 | KMT2C | Ssm | 10 | 122 | 8.2% | cbioportal |
| 29 | ZFHX4 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 16 | ADGRV1 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 23 | NEB | Ssm | 9 | 122 | 7.4% | cbioportal |
| 19 | CDH1 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 27 | SPTA1 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 26 | RYR2 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 28 | TENM4 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 22 | FSIP2 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 21 | DNAH9 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 18 | BLTP1 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 24 | PCLO | Ssm | 9 | 122 | 7.4% | cbioportal |
| 25 | PTEN | Ssm | 9 | 122 | 7.4% | cbioportal |
| 17 | AHNAK2 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 20 | DNAH11 | Ssm | 9 | 122 | 7.4% | cbioportal |
| 40 | MUC17 | Ssm | 8 | 122 | 6.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-05