Other
Neoplasm by Site
CI-CAN-00000003Explore in graph →
Non-malignant20,474 active trials253 approved drugs3,567 evidence items
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Other
CI-CAN-00000003Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
408 cases with simple somatic mutation data · 413 cases total · 2026-01-19 · mapped to Bladder Urothelial Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 202 |
| 408 |
| 49.5% |
| cbioportal |
| 2 | TTN | Ssm | 176 | 408 | 43.1% | cbioportal |
| 3 | KMT2D | Ssm | 109 | 408 | 26.7% | cbioportal |
| 4 | KDM6A | Ssm | 104 | 408 | 25.5% | cbioportal |
| 5 | MUC16 | Ssm | 103 | 408 | 25.2% | cbioportal |
| 6 | ARID1A | Ssm | 100 | 408 | 24.5% | cbioportal |
| 7 | PIK3CA | Ssm | 86 | 408 | 21.1% | cbioportal |
| 8 | SYNE1 | Ssm | 80 | 408 | 19.6% | cbioportal |
| 9 | RB1 | Ssm | 72 | 408 | 17.6% | cbioportal |
| 10 | KMT2C | Ssm | 69 | 408 | 16.9% | cbioportal |
| 11 | RYR2 | Ssm | 69 | 408 | 16.9% | cbioportal |
| 12 | HMCN1 | Ssm | 66 | 408 | 16.2% | cbioportal |
| 15 | MACF1 | Ssm | 60 | 408 | 14.7% | cbioportal |
| 14 | FAT4 | Ssm | 60 | 408 | 14.7% | cbioportal |
| 13 | EP300 | Ssm | 60 | 408 | 14.7% | cbioportal |
| 16 | FLG | Ssm | 58 | 408 | 14.2% | cbioportal |
| 17 | FGFR3 | Ssm | 56 | 408 | 13.7% | cbioportal |
| 18 | STAG2 | Ssm | 56 | 408 | 13.7% | cbioportal |
| 19 | ELF3 | Ssm | 55 | 408 | 13.5% | cbioportal |
| 20 | CSMD3 | Ssm | 53 | 408 | 13% | cbioportal |
| 21 | ATM | Ssm | 51 | 408 | 12.5% | cbioportal |
| 22 | OBSCN | Ssm | 50 | 408 | 12.3% | cbioportal |
| 23 | NEB | Ssm | 49 | 408 | 12% | cbioportal |
| 24 | CUBN | Ssm | 48 | 408 | 11.8% | cbioportal |
| 27 | SYNE2 | Ssm | 47 | 408 | 11.5% | cbioportal |
| 26 | DNAH5 | Ssm | 47 | 408 | 11.5% | cbioportal |
| 25 | BIRC6 | Ssm | 47 | 408 | 11.5% | cbioportal |
| 29 | ERBB2 | Ssm | 46 | 408 | 11.3% | cbioportal |
| 30 | XIRP2 | Ssm | 46 | 408 | 11.3% | cbioportal |
| 31 | ZFHX4 | Ssm | 46 | 408 | 11.3% | cbioportal |
Data updated 21 days agoSource updated 2026-01-19