ARID1B

AT-rich interaction domain 1B

Explore in graph →CI-GENE-00011299HGNC:18040 ENSG00000049618 NCBI 57492 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
ARID1A Mutation + ARID1B MutationARID1A ARID1B1
(functional)	—UNRESOLVED	Functional	B	Supports Loss Of Function	3	submitted	EID12642 Concurrent inactivating mutations in ARID1A and ARID1B were identified in 12 of 24 BRG1/INI1-intact dedifferentiated endometrial or ovarian carcinomas, with all co-mutated tumours showing complete los… (full text at CIViC) PMID 27562491 · Coatham et al., 2016 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (200)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved200 cohort rows (showing 50, sorted by frequency) · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Endometrial Carcinoma MSI (MSK, Clin Cancer Res 2022) ucec_ccr_msk_2022	Endometrial Carcinoma	Ssm

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.