Gene
ITGB3
integrin subunit beta 3
Explore in graph →CI-GENE-00006432HGNC:6156 ENSG00000259207 NCBI 3690 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24487277
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Clear Cell Carcinoma (IRC, Nat Genet 2014) ccrcc_irc_2014 | Clear Cell Renal Cell Carcinoma | Ssm | 11 | 78 | 14.1% | 14 | cbioportal |
| Glioblastoma (TCGA, Nature 2008) gbm_tcga_pub | Diffuse Glioma | Ssm | 3 | 91 | 3.3% | 17 | cbioportal |
| Breast Invasive Carcinoma (Sanger, Nature 2012) brca_sanger | Invasive Breast Carcinoma | Ssm | 3 | 100 | 3% | 127 | cbioportal |
| Triple-Negative Breast Cancer (FUSCC, Cell Research 2020) brca_fuscc_2020 | Invasive Breast Carcinoma | Ssm | 1 | 69 | 1.4% | 191 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.