Gene
REST
RE1 silencing transcription factor
Explore in graph →CI-GENE-00023347HGNC:9966 ENSG00000084093 NCBI 5978 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (10)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36355783
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (MSK, Cancer Discovery 2022) coadread_mskresistance_2022 | Colorectal Adenocarcinoma | Ssm | 7 | 19 | 36.8% | 186 | cbioportal |
| Prostate Cancer MDA PCa PDX (MD Anderson, Clin Cancer Res 2024) prad_msk_mdanderson_2023 | unmapped | Ssm | 7 | 44 | 15.9% | 196 | cbioportal |
| Urothelial Cancer Patient Derived Organoids (MSK, 2025) blca_pdx_msk_2025 | Bladder Urothelial Carcinoma | Ssm | 4 | 34 | 11.8% | 165 | cbioportal |
| Endometrial cancer HR-positive (MSK, 2024) uec_msk_2024 | Endometrial Carcinoma | Ssm | 1 | 9 | 11.1% | 108 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.