Gene
NHS
NHS actin remodeling regulator
Explore in graph →CI-GENE-00016742HGNC:7820 ENSG00000188158 NCBI 4810 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (16)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34910928
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pre-cancer Colorectal Polyps (HTAN Vanderbilt, Cell 2021) crc_hta11_htan_2021 | Colorectal Adenocarcinoma | Ssm | 9 | 30 | 30% | 111 | cbioportal |
| Stomach Adenocarcinoma (U Tokyo, Nat Genet 2014) stad_utokyo | Gastric Adenocarcinoma | Ssm | 2 | 30 | 6.7% | 99 | cbioportal |
| Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA, Firehose Legacy) cesc_tcga | Cervical Squamous Cell Carcinoma | Ssm | 12 | 194 | 6.2% | 55 | cbioportal |
| Bladder Urothelial Carcinoma (BGI, Nat Genet 2013) blca_bgi | Bladder Urothelial Carcinoma | Ssm | 6 | 99 | 6.1% | 45 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.