Gene
SETDB1
SET domain bifurcated histone lysine methyltransferase 1
Explore in graph →CI-GENE-00030404HGNC:10761 ENSG00000143379 NCBI 9869 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (26)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 38630790
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pleural Mesothelioma (MSK, Clin Cancer Res 2024) plmeso_msk_2024 | Pleural Mesothelial Neoplasm | Ssm | 4 | 4 | 100% | 3 | cbioportal |
| CDDP Integrative Analysis of Lung Adenocarcinoma (Phase 2) CDDP_EAGLE-1 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.