Gene
IGF1
insulin like growth factor 1
Explore in graph →CI-GENE-00005487HGNC:5464 ENSG00000017427 NCBI 3479 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (13)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36355783
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (MSK, Cancer Discovery 2022) coadread_mskresistance_2022 | Colorectal Adenocarcinoma | Ssm | 10 | 22 | 45.5% | 21 | cbioportal |
| Sarcoma (MSK, 2026) lms_msk_2026 | unmapped | Ssm | 2 | 41 | 4.9% | 190 | cbioportal |
| Serous Ovarian Cancer (MSK, 2025) ovarian_msk_2025 | unmapped | Ssm | 1 | 31 | 3.2% | 42 | cbioportal |
| Non-Small Cell Lung Cancer (MSK, 2026) alk_msk_2026 | Lung Non-Small Cell Carcinoma | Ssm | 2 | 90 | 2.2% | 184 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.