Gene
PLXNA2
plexin A2
Explore in graph →CI-GENE-00020193HGNC:9100 ENSG00000076356 NCBI 5362 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (21)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 31278255
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Upper Tract Urothelial Carcinoma (Cornell/Baylor/MDACC, Nat Commun 2019) utuc_cornell_baylor_mdacc_2019 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 4 | 37 | 10.8% | 15 | cbioportal |
| Esophageal Carcinoma (TCGA, Firehose Legacy) esca_tcga | Esophageal Adenocarcinoma | Ssm | 12 | 185 | 6.5% | 189 | cbioportal |
| Ampullary Carcinoma (Baylor College of Medicine, Cell Reports 2016) ampca_bcm_2016 | Ampulla of Vater Carcinoma | Ssm | 9 | 160 | 5.6% | 87 | cbioportal |
| Neuroendocrine Prostate Cancer (Multi-Institute, Nat Med 2016) nepc_wcm_2016 | Prostate Adenocarcinoma | Ssm | 6 | 114 | 5.3% | 53 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.