Gene
CDKN2C
cyclin dependent kinase inhibitor 2C
Explore in graph →CI-GENE-00040783HGNC:1789 ENSG00000123080 NCBI 1031 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (32)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28472509
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytoma (MSK, Neuro Oncol 2017) odg_msk_2017 | Diffuse Glioma | Ssm | 3 | 22 | 13.6% | 11 | cbioportal |
| Atypical Small Cell Lung Cancer (MSK, Cancer Discov 2024) asclc_msk_2024 | unmapped | Ssm | 4 | 31 | 12.9% | 7 | cbioportal |
| Sarcoma (MSK, 2026) lms_msk_2026 | unmapped | Ssm | 2 | 41 | 4.9% | 163 | cbioportal |
| Glioma (MSK, Nature 2019) glioma_msk_2018 | Diffuse Glioma | Ssm | 3 | 91 | 3.3% | 117 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.