Gene
CD79B
CD79b molecule
Explore in graph →CI-GENE-00040530HGNC:1699 ENSG00000007312 NCBI 974 CIViC Cancer geneApproved
Curated evidence
Clinical evidence (2)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 29641966
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CD79B MUTATION2 | ||||||||
| (prognostic) | Diffuse Large B-Cell LymphomaCURATED_BROADER | Prognostic | A | Supports Better Outcome | 4 | submitted | EID8262MCD subtype is based on the co-occurrence of MYD88.L265P and CD79B mutations. PMID 29641966 · Schmitz et al., 2018 · Open in CIViC | civic |
| (diagnostic) | MCD Diffuse Large B-Cell Lymphoma | Diagnostic | E | Supports Positive | 3 | submitted | EID11822This is one of the genetic features of this subgroup PMID 32289277 · Wright et al., 2020 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (24)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Kidney Renal Papillary Cell Carcinoma TCGA-KIRP | Papillary Renal Cell Carcinoma | Ssm |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.