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CancerIndex

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Head and Neck Squamous Cell Carcinoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Malignant Head and Neck Neoplasm
Head and Neck Carcinoma
Head and Neck Squamous Cell Carcinoma

Subtype

Head and Neck Squamous Cell Carcinoma

CI-CAN-00002836HNSCC · SCCHNExplore in graph →

591 active trials6 approved drugs53 evidence items

NCIt: C34447
OncoTree: HNSC
DOID: 5520
UMLS CUI: C1168401
MeSH: D000077195
Other: 1 more code

Overview
Statistics
Survival
Genomics9
Variants & evidence53
Drugs27
Trials1588
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A squamous cell carcinoma that arises from any of the following anatomic sites: lip and oral cavity, nasal cavity, paranasal sinuses, pharynx, larynx, and salivary glands.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Head and Neck CarcinomaSubtype
Squamous Cell CarcinomaHistology

Children (16)

ncit

ASPH-Positive Head and Neck Squamous Cell Carcinoma
Head and Neck Basaloid Squamous Cell Carcinoma6 sub
Head and Neck Cutaneous Squamous Cell Carcinoma6 sub
Head and Neck Keratinizing Squamous Cell Carcinoma7 sub
Head and Neck Mucosal Squamous Cell Carcinoma6 sub
Head and Neck Non-Keratinizing Squamous Cell Carcinoma4 sub
Lacrimal Drainage System Squamous Cell Carcinoma

Anatomy

Anatomical sites

Head and NeckC12418

Record

Identity

CancerIndex ID: CI-CAN-00002836
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 5
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

2 sub

Lip and Oral Cavity Squamous Cell Carcinoma2 sub

Orbital Squamous Cell Carcinoma1 sub

Salivary Gland Squamous Cell Carcinoma3 sub

oncotree

Head and Neck Squamous Cell Carcinoma of Unknown Primary
Hypopharyngeal Squamous Cell Carcinoma7 sub
Laryngeal Squamous Cell Carcinoma8 sub
Oral Cavity Squamous Cell Carcinoma7 sub
Oropharynx Squamous Cell Carcinoma
Sinonasal Non-Keratinizing Squamous Cell Carcinoma2 sub

134 descendants in total; counters on this page aggregate over all of them.

1,588 / 591

Publications (all / 5y)

15,841 / 9,035

Evidence items

53

Genes / variants

239 / 36

Drugs (any / approved)

27 / 6

Genomic cohorts

9

Epidemiology / survival obs.

0 / 0

Data updated 18 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (5)

Squamous Cell Carcinoma of Head and Neckmesh_heading · MeSH
Carcinoma, Squamous Cell of Head and Necksynonym · MeSH
Head and Neck Squamous Cell Carcinomasynonym · OncoTree
Squamous Cell Carcinoma of Head and Necksynonym · NCIt
Squamous Cell Carcinoma of the Head and Necksynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials591countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #65 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials313countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #66 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items53countaccepted CIViC items · entity + descendantscivicComputedrank #82 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months1,217countPubMed records · stored query · 12-month windowpubmedComputedrank #94 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts9countopen GDC projects · entity + descendantsgdcComputedrank #108 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 18 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants